The AGC kinase subfamily of protein kinases contains 60 members, including PKA, PKG
and PKC. The family comprises some intensely examined protein kinases (such as Akt, S6K …

Activity-dependent plasticity of synaptic structure and function plays an essential role in
neuronal development and in cognitive functions including learning and memory. The …

Natriuretic peptides are a family of three structurally related hormone/paracrine factors. Atrial
natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are secreted from the cardiac …

Recent data have demonstrated a biochemical sequence of events in the rat hippocampus
that is necessary for memory formation of inhibitory avoidance behavior. The sequence …

This review covers recent developments in the cellular neurophysiology of retrograde
signaling in the mammalian central nervous system. Normally at a chemical synapse a …

Naturally occuring polymorphisms in behavior are difficult to map genetically and thus are
refractory to molecular characterization. An exception is the foraging gene (for), a gene that …

Over the past few years, a wealth of biochemical and functional data have been gathered on
mammalian cGMP-dependent protein kinases (cGKs). In mammals, three different kinases …

The growth and behavior of higher organisms depend on the accurate perception and
integration of sensory stimuli by the nervous system. We show that defects in sensory …

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly
understood, a problem that is exacerbated by the enormous genetic heterogeneity of this …

Long-term potentiation (LTP) in the hippocampus has an early phase (E-LTP) that can be
induced by one-or two-train tetanization, lasts∼ 1 hr, and is cAMP-dependent protein kinase …