Paleoproteomics

C Warinner, K Korzow Richter, MJ Collins - Chemical reviews, 2022 - ACS Publications
Paleoproteomics, the study of ancient proteins, is a rapidly growing field at the intersection of
molecular biology, paleontology, archaeology, paleoecology, and history. Paleoproteomics …

The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics

LK Pino, BC Searle, JG Bollinger… - Mass spectrometry …, 2020 - Wiley Online Library
Skyline is a freely available, open‐source Windows client application for accelerating
targeted proteomics experimentation, with an emphasis on the proteomics and mass …

A review on mass spectrometry-based quantitative proteomics: Targeted and data independent acquisition

V Vidova, Z Spacil - Analytica chimica acta, 2017 - Elsevier
Mass spectrometry (MS) based proteomics have achieved a near-complete proteome
coverage in humans and in several other organisms, producing a wealth of information …

DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics

CC Tsou, D Avtonomov, B Larsen, M Tucholska… - Nature …, 2015 - nature.com
As a result of recent improvements in mass spectrometry (MS), there is increased interest in
data-independent acquisition (DIA) strategies in which all peptides are systematically …

Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach

SA Carr, SE Abbatiello, BL Ackermann… - Molecular & Cellular …, 2014 - ASBMB
Adoption of targeted mass spectrometry (MS) approaches such as multiple reaction
monitoring (MRM) to study biological and biomedical questions is well underway in the …

Fluid and ion transfer across the blood–brain and blood–cerebrospinal fluid barriers; a comparative account of mechanisms and roles

SB Hladky, MA Barrand - Fluids and Barriers of the CNS, 2016 - Springer
The two major interfaces separating brain and blood have different primary roles. The
choroid plexuses secrete cerebrospinal fluid into the ventricles, accounting for most net fluid …

[HTML][HTML] Challenges and perspectives of metaproteomic data analysis

R Heyer, K Schallert, R Zoun, B Becher, G Saake… - Journal of …, 2017 - Elsevier
In nature microorganisms live in complex microbial communities. Comprehensive taxonomic
and functional knowledge about microbial communities supports medical and technical …

Advanced cell culture techniques for cancer drug discovery

CJ Lovitt, TB Shelper, VM Avery - Biology, 2014 - mdpi.com
Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

Forensic proteomics

GJ Parker, HE McKiernan, KM Legg… - Forensic Science …, 2021 - Elsevier
Protein is a major component of all biological evidence, often the matrix that embeds other
biomolecules such as polynucleotides, lipids, carbohydrates, and small molecules. The …

Application of targeted mass spectrometry in bottom-up proteomics for systems biology research

NP Manes, A Nita-Lazar - Journal of proteomics, 2018 - Elsevier
The enormous diversity of proteoforms produces tremendous complexity within cellular
proteomes, facilitates intricate networks of molecular interactions, and constitutes a …