Macrophages are a heterogeneous group of cells that are capable of carrying out distinct
functions in different tissues, as well as in different locations within a given tissue. Some of …

The blood-labyrinth barrier (BLB) in the stria vascularis is a highly specialized capillary
network that controls exchanges between blood and the intrastitial space in the cochlea. The …

Macrophages are abundant in the cochlea; however, their role in hearing loss is not well
understood. Insults to the cochlea, such as noise or insertion of a cochlear implant, cause an …

Both age-related hearing loss (ARHL) and age-related loss in vestibular function (ARVL) are
prevalent conditions with deleterious consequences on the health and quality of life. Age …

The stria vascularis (SV) is a highly vascularized tissue lining the lateral wall of the cochlea.
The SV maintains cochlear fluid homeostasis, generating the endocochlear potential that is …

The cochlea has an immune environment dominated by macrophages under resting
conditions. When stressed, circulating monocytes enter the cochlea. These immune …

Age-related hearing loss, or presbyacusis, is a common degenerative disorder affecting
communication and quality of life for millions of older adults. Multiple pathophysiologic …

Acoustic trauma is an important physical factor leading to cochlear damage and hearing
impairments. Inflammation responds to this kind of cochlear damage stress. Macrophages …

Macrophages are the main intrinsic immune cells in the cochlea; they can be activated and
play a complicated role after cochlear injury. Many studies have shown that the number of …

This review aims to provide a conceptual and theoretical overview of the association
between gut dysbiosis and hearing loss. Hearing loss is a global health issue; the World …