Potent candidates for Targeted Auger Therapy: Production and radiochemical considerations

D Filosofov, E Kurakina, V Radchenko - Nuclear Medicine and Biology, 2021 - Elsevier
Abstract Targeted Auger Therapy represents great potential for the therapy of diseases
which require a high degree of selectivity on the cellular level (eg for therapy of metastatic …

External and internal radiation therapy: past and future directions

M Sadeghi, M Enferadi, A Shirazi - Journal of cancer research and …, 2010 - journals.lww.com
Cancer is a leading cause of morbidity and mortality in the modern world. Treatment
modalities comprise radiation therapy, surgery, chemotherapy and hormonal therapy …

Meitner-Auger Electron Emitters for Targeted Radionuclide Therapy: Mercury-197m/g and Antimony-119.

P Randhawa, AP Olson, S Chen… - Current …, 2021 - benthamdirect.com
Targeted Radionuclide Therapies (TRTs) based on Auger emitting radionuclides have the
potential to deliver extremely selective therapeutic payloads on the cellular level. However …

Chemistry of Antimony in Radiopharmaceutical Development: Unlocking the Theranostic Potential of Sb Isotopes

A Grundmane, V Radchenko, CF Ramogida - ChemPlusChem, 2024 - Wiley Online Library
Abstract Antimony‐119 (119Sb) holds promise for radiopharmaceutical therapy (RPT),
emitting short‐range Auger and conversion electrons that can deliver cytotoxic radiation on …

Sustainable production of radionuclidically pure antimony-119

AP Olson, FA Verich, PA Ellison… - EJNMMI …, 2024 - Springer
Background Radiopharmaceutical therapy (RPT) uses radionuclides that decay via one of
three therapeutically relevant decay modes (alpha, beta, and internal conversion (IC)/Auger …

Production and radiochemistry of antimony-120m: Efforts toward Auger electron therapy with 119Sb

TI Kostelnik, AP Olson, A Grundmane, PA Ellison… - Nuclear Medicine and …, 2023 - Elsevier
Abstract Targeted Meitner-Auger Therapy (TMAT) has potential for personalized treatment
thanks to its subcellular dosimetric selectivity, which is distinct from the dosimetry of β− and α …

Nuclear model calculations on the production of 119Sb via various nuclear reactions

M Sadeghi, M Enferadi - Annals of Nuclear Energy, 2011 - Elsevier
Only very few radionuclides exist that decay exclusively by EC-mode without accompanying
radiation, 119Sb is one of them. Auger emitter 119Sb (T1/2= 38.9 h, IEC= 100%) is a potent …

Large-Scale Production of 119mTe and 119Sb for Radiopharmaceutical Applications

KT Bennett, SE Bone, AC Akin, ER Birnbaum… - ACS central …, 2019 - ACS Publications
Radionuclides find widespread use in medical technologies for treating and diagnosing
disease. Among successful and emerging radiotherapeutics, 119Sb has unique potential in …

Cross sections and production yields of 117mSn and other radionuclides generated in natural and enriched antimony with protons up to 145 MeV

SV Ermolaev, BL Zhuikov, VM Kokhanyuk… - Radiochimica …, 2020 - degruyter.com
Cross sections of a prospective medical radionuclide 117mSn along with 113Sn, 120m,
122Sb, 111,114 mIn and 118,119 m, 119g, 121m, 121g, 123mTe generated in natural and …

Radionuclides emitting short-range particles and modular nanotransporters for their delivery to target cancer cells

AS Sobolev, RA Aliev… - Russian Chemical Reviews, 2016 - iopscience.iop.org
The survey considers radionuclides emitting short-range particles. Methods for the
production of most promising $\alpha $-and Auger electron emitters and their applications in …