Cancer is a leading cause of morbidity and mortality in the modern world. Treatment modalities comprise radiation therapy, surgery, chemotherapy and hormonal therapy …
Targeted Radionuclide Therapies (TRTs) based on Auger emitting radionuclides have the potential to deliver extremely selective therapeutic payloads on the cellular level. However …
A Grundmane, V Radchenko, CF Ramogida - ChemPlusChem, 2024 - Wiley Online Library
Abstract Antimony‐119 (119Sb) holds promise for radiopharmaceutical therapy (RPT), emitting short‐range Auger and conversion electrons that can deliver cytotoxic radiation on …
AP Olson, FA Verich, PA Ellison… - EJNMMI …, 2024 - Springer
Background Radiopharmaceutical therapy (RPT) uses radionuclides that decay via one of three therapeutically relevant decay modes (alpha, beta, and internal conversion (IC)/Auger …
TI Kostelnik, AP Olson, A Grundmane, PA Ellison… - Nuclear Medicine and …, 2023 - Elsevier
Abstract Targeted Meitner-Auger Therapy (TMAT) has potential for personalized treatment thanks to its subcellular dosimetric selectivity, which is distinct from the dosimetry of β− and α …
Only very few radionuclides exist that decay exclusively by EC-mode without accompanying radiation, 119Sb is one of them. Auger emitter 119Sb (T1/2= 38.9 h, IEC= 100%) is a potent …
Radionuclides find widespread use in medical technologies for treating and diagnosing disease. Among successful and emerging radiotherapeutics, 119Sb has unique potential in …
Cross sections of a prospective medical radionuclide 117mSn along with 113Sn, 120m, 122Sb, 111,114 mIn and 118,119 m, 119g, 121m, 121g, 123mTe generated in natural and …
AS Sobolev, RA Aliev… - Russian Chemical Reviews, 2016 - iopscience.iop.org
The survey considers radionuclides emitting short-range particles. Methods for the production of most promising $\alpha $-and Auger electron emitters and their applications in …