The diagnosis and treatment of multiple myeloma has changed dramatically in the past
decade. The disease definition has been updated to include highly specific biomarkers in …

The number of patients with bone metastasis increases as medical management and
surgery improve the overall survival of patients with cancer. Bone metastasis can cause …

Background. Spinal metastases frequently arise in patients with cancer. Modern oncology
provides numerous treatment options that include effective systemic, radiation, and surgical …

Purpose To provide evidence-based guidance on the optimum management of chronic pain
in adult cancer survivors. Methods An ASCO-convened expert panel conducted a systematic …

Purpose Standardized indications for treatment of tumor-related spinal instability are
hampered by the lack of a valid and reliable classification system. The objective of this study …

Purpose The aim of the International Myeloma Working Group was to develop practice
recommendations for the management of multiple myeloma (MM)–related bone disease …

Study Design. Systematic literature review. Objective. To evaluate the safety and efficacy of
vertebroplasty and kyphoplasty using the data presented in published clinical studies, with …

Compression fractures affect many individuals worldwide. An estimated 1.5 million vertebral
compression fractures occur every year in the US. They are common in elderly populations …

With continued growth of the elderly population and improvements in cancer therapies, the
number of patients with symptomatic spinal metastases is likely to increase, and this is a …

Abstract Treatment paradigms for patients with spine metastases have evolved significantly
over the past decade. Incorporating stereotactic radiosurgery into these paradigms has been …