Epigenetic modifications are chemical groups in our DNA (and chromatin) that determine
which genes are active and which are shut off. Importantly, they integrate environmental …

Circadian rhythms integrate a finely tuned network of biological processes recurring every
24 h, intricately coordinating the machinery of all cells. This self-regulating system plays a …

Lead (Pb) is a neurotoxicant with early life exposure linked to long-term health effects. Piwi-
interacting RNAs (piRNAs) are small non-coding RNAs that associate with PIWIL proteins to …

Introduction The epidemiological investigation of congenital anomalies (CA) represents a
challenge due to the multiplicity of associated risk factors, notably environmental ones. The …

Neutrophils are the most abundant leukocytes in humans and essential for innate immune
responses despite a short lifespan in the bloodstream. A complex and tightly regulated …

Epidemiological studies show that exposure to the organochlorine pesticide dieldrin is
associated with increased risk of Parkinson's disease (PD). Animal studies support a link …

Humans are exposed to an increasing number and diversity of chemicals from the
environment. These include chemicals released into the environment, in food, from use of …

The adverse effects of personalized toxicity are in an intricate balance with the intended
efficacy of personalized medicine, but they are equally important in terms of other exposures …

RÉSUMÉ L'exposome correspond à l'ensemble des expositions, notamment à des agents
chimiques, biologiques, physiques, des stress psycho-sociaux subies par un individu tout au …