Matrix metalloproteinases (MMPs) serve as prognostic factors in several pathophysiological
conditions, including chronic wounds. Therefore, they are considered important therapeutic …

Targeting epidermal growth factor receptor (EGFR) mutants is a promising strategy for
treating non-small cell lung cancer (NSCLC). This study focused on the computational …

Melatonin receptors MT1 and MT2 are G protein-coupled receptors that mediate the effects
of melatonin, a hormone involved in circadian rhythms and other physiological functions …

The present study focused on the design and synthesis of two classes of hydrazones of
isatin derivatives bearing morpholine and piperazine units (IHP1-IHP6 and IHM1-IHM6). The …

The rational synthesis, antifungal activity in vitro, and in silico ADME/pharmacokinetic study
of imidazole clubbed pyrazole and isoxazole derivatives has been described in this article. A …

Background Plant formulations with antidiabetic and antioxidant properties have recently
gained popularity due to their lower cost and lesser side effects. Guggul gum is one such …

Current study establishes synthesis of AgNPs from Solanum trilobatum by a simple
microwave protocol. Major phytoconstituents such as solasodine, solanine, solanidine were …

Introduction Recently, imidazooxazines have attracted more attention due to their
therapeutic potential against tuberculosis (TB). The present study aimed to identify and …

The HER family consists of multidomain proteins that are critical in regulating several
biological functions. Among the HER proteins, HER2 is overexpressed in breast cancer cells …

Abstract In Salmonella Typhimurium, efflux pump proteins, such as AcrD actively expel
drugs and hazardous chemicals from bacterial cells, resulting in treatment failure and the …