Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

The Global Burden of Disease Study identified cardiovascular risk factors as leading causes
of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism …

Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and
its antiatherogenic properties support cardiovascular homeostasis. Diminished NO …

Oxidative stress has long been implicated in cardiovascular disease, but more recently, the
role of reactive oxygen species (ROS) in normal physiological signaling has been …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

The prevalence of cardiovascular diseases is significantly increased in the older population.
Risk factors and predictors of future cardiovascular events such as hypertension …

Oxidative stress is increased in systemic lupus erythematosus (SLE), and it contributes to
immune system dysregulation, abnormal activation and processing of cell-death signals …

Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide
dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely, have potent vasodilator …

Nitric oxide (NO) is a gaseous signaling molecule and effector in various biological
processes. In mammalian cells, NO is produced by a family of NO synthases (NOS). Three …

Environmental pollution and non-chemical stressors such as mental stress or traffic noise
exposure are increasingly accepted as health risk factors with substantial contribution to …