Perinatal stroke: mapping and modulating developmental plasticity

A Kirton, MJ Metzler, BT Craig, A Hilderley… - Nature Reviews …, 2021 - nature.com
Most cases of hemiparetic cerebral palsy are caused by perinatal stroke, resulting in lifelong
disability for millions of people. However, our understanding of how the motor system …

Perinatal stroke syndromes: Similarities and diversities in aetiology, outcome and management

J Fluss, M Dinomais, S Chabrier - European Journal of paediatric …, 2019 - Elsevier
With a birth-prevalence of 37–67/100,000 (mostly term-born), perinatal stroke encompasses
distinct disease-states with diverse causality, mechanism, time of onset, mode of …

Alterations in cortical morphometry of the contralesional hemisphere in children, adolescents, and young adults with perinatal stroke

K Shinde, BT Craig, J Hassett, N Dlamini, BL Brooks… - Scientific Reports, 2023 - nature.com
Perinatal stroke causes most hemiparetic cerebral palsy and cognitive dysfunction may co-
occur. Compensatory developmental changes in the intact contralesional hemisphere may …

Developmental neuroplasticity of the white matter connectome in children with perinatal stroke

BT Craig, A Hilderley, E Kinney-Lang, X Long… - Neurology, 2020 - AAN Enterprises
Objective To employ diffusion imaging connectome methods to explore network
development in the contralesional hemisphere of children with perinatal stroke and its …

Structural connectivity of the sensorimotor network within the non-lesioned hemisphere of children with perinatal stroke

BT Craig, E Kinney-Lang, AJ Hilderley, HL Carlson… - Scientific Reports, 2022 - nature.com
Perinatal stroke occurs early in life and often leads to a permanent, disabling weakness to
one side of the body. To test the hypothesis that non-lesioned hemisphere sensorimotor …

Ipsilesional volume loss of basal ganglia and thalamus is associated with poor hand function after ischemic perinatal stroke

N Ilves, S Lõo, N Ilves, R Laugesaar, D Loorits, P Kool… - BMC neurology, 2022 - Springer
Background Perinatal stroke (PS) is the leading cause of hemiparetic cerebral palsy (CP).
Involvement of the corticospinal tract on neonatal magnetic resonance imaging (MRI) is …

Perinatal ischemic stroke: etiology and imaging

NV Stence, DM Mirsky… - Clinics in …, 2022 - perinatology.theclinics.com
Perinatal ischemic stroke is common, exceeding the risk of childhood stroke 10-fold. 1 Most
cases of unilateral hemiparesis are due to perinatal stroke. 2 Early identification of affected …

The thalamus and basal ganglia are smaller in children with epilepsy after perinatal stroke

U Vaher, N Ilves, N Ilves, R Laugesaar… - Frontiers in …, 2023 - frontiersin.org
Background Epilepsy is one of the most serious consequences of perinatal stroke. Epilepsy
itself has been proposed as a risk factor for impaired cognitive, language, and behavioral …

[HTML][HTML] Structural and functional connectivity of motor circuits after perinatal stroke: A machine learning study

HL Carlson, BT Craig, AJ Hilderley, J Hodge… - NeuroImage: Clinical, 2020 - Elsevier
Developmental neuroplasticity allows young brains to adapt via experiences early in life and
also to compensate after injury. Why certain individuals are more adaptable remains …

Imaging developmental and interventional plasticity following perinatal stroke

BT Craig, A Hilderley, A Kirton… - Canadian Journal of …, 2021 - cambridge.org
Perinatal stroke occurs around the time of birth and leads to lifelong neurological disabilities
including hemiparetic cerebral palsy. Magnetic resonance imaging (MRI) has revolutionized …