W Li, CJ Hao, ZH Hao, J Ma, QC Wang… - Pigment Cell & …, 2022 - Wiley Online Library
Hermansky–Pudlak syndrome (HPS) is characterized by defects of multiple tissue‐specific lysosome‐related organelles (LROs), typically manifesting with oculocutaneous albinism or …
L Dobson, C Gerdán, S Tusnády… - Nucleic Acids …, 2024 - academic.oup.com
Abstract The UNIfied database of TransMembrane Proteins (UniTmp) is a comprehensive and freely accessible resource of transmembrane protein structural information at different …
AC Norris, EM Yazlovitskaya, L Zhu, BS Rose… - Scientific Reports, 2024 - nature.com
Genetic association studies have linked ATP10A and closely related type IV P-type ATPases (P4-ATPases) to insulin resistance and vascular complications, such as atherosclerosis …
Neural systems encode information in the frequency of action potentials, which is then decoded by synaptic transmission. However, the rapid, synchronous release of …
Cells internalize proteins and lipids in the plasma membrane (PM) and solutes in the extracellular space by endocytosis. The removal of PM by endocytosis is constantly …
AC Norris, AJ Mansueto, M Jimenez… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abstract Type IV P-type ATPases (P4-ATPases) are a family of transmembrane enzymes that translocate lipid substrates from the outer to the inner leaflet of biological membranes and …
E Purev, K Bahmed, B Kosmider - Biomolecules, 2024 - mdpi.com
Lung organoids display a tissue-specific functional phenomenon and mimic the features of the original organ. They can reflect the properties of the cells, such as morphology, polarity …
The lamellar body (LB) of the alveolar type II (ATII) cell is a lysosome-related organelle (LRO) that contains surfactant, a complex mix of mainly lipids and specific surfactant …
C Inoue, K Mukai, T Matsudaira, J Nakayama… - Scientific Reports, 2023 - nature.com
Yes-associated protein (YAP) is a transcriptional coactivator that is essential for the malignancy of various cancers. We have previously shown that YAP activity is positively …