Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging in Caenorhabditis elegans

KRS Doering, G Ermakova, S Taubert - Frontiers in Physiology, 2023 - frontiersin.org
The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which
perform diverse functions in development and physiology. One of the best characterized of …

In vitro and in silico assessment of endocrine disrupting effects of food contaminants through pregnane X receptor

Y Liang, Q Jiang, Y Gong, Y Yu, H Zou, J Zhao… - Food and Chemical …, 2023 - Elsevier
As a promiscuous xenobiotic receptor, pregnane X receptor (PXR) has been confirmed to
participate in numerous physiological process. In addition to the conventional …

[HTML][HTML] Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states

B MacTavish, D Zhu, J Shang, Q Shao, ZJ Yang… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Nuclear receptors (NRs) are thought to dynamically alternate between transcriptionally
active and repressive conformations, which are stabilized upon ligand binding. Most NR …

Studie av retinoid X reseptorer (Rxr) og Rxr-signalveier i Atlanterhavstorsk (Gadus morhua) ved bruk av immunokjemiske of ex vivo teknikker

EM Christiansen - 2023 - bora.uib.no
Nuclear receptors (NRs) comprise a large superfamily of ligand-activated transcription
factors. Many NRs facilitate gene expression through heterodimeric binding to retinoid X …