Antibiotic resistance and persistence—Implications for human health and treatment perspectives

M Huemer, S Mairpady Shambat, SD Brugger… - EMBO …, 2020 - embopress.org
Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Genomic surveillance for antimicrobial resistance—a One Health perspective

SP Djordjevic, VM Jarocki, T Seemann… - Nature Reviews …, 2024 - nature.com
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …

Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

E Rossi, R La Rosa, JA Bartell, RL Marvig… - Nature Reviews …, 2021 - nature.com
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …

Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

[HTML][HTML] Towards monitoring of antimicrobial resistance in the environment: for what reasons, how to implement it, and what are the data needs?

J Bengtsson-Palme, A Abramova, TU Berendonk… - Environment …, 2023 - Elsevier
Antimicrobial resistance (AMR) is a global threat to human and animal health and well-
being. To understand AMR dynamics, it is important to monitor resistant bacteria and …

Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review

MS Mulani, EE Kamble, SN Kumkar… - Frontiers in …, 2019 - frontiersin.org
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

CL Gorrie, M Mirčeta, RR Wick, LM Judd… - Nature …, 2022 - nature.com
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases …

Emergent crisis of antibiotic resistance: A silent pandemic threat to 21st century

F Akram, M Imtiaz, I ul Haq - Microbial pathogenesis, 2023 - Elsevier
Antibiotic resistance has become an indispensably alarming menace to the global
community. The primary factors are overuse and abuse of antibiotics, lack of novel …

Implant infections: adhesion, biofilm formation and immune evasion

CR Arciola, D Campoccia, L Montanaro - Nature reviews microbiology, 2018 - nature.com
Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …