A scoping review of the pathophysiology of COVID-19
COVID-19 is a highly heterogeneous and complex medical disorder; indeed, severe COVID-
19 is probably amongst the most complex of medical conditions known to medical science …
19 is probably amongst the most complex of medical conditions known to medical science …
Mast cell biology at molecular level: a comprehensive review
D Elieh Ali Komi, S Wöhrl, L Bielory - Clinical reviews in allergy & …, 2020 - Springer
Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone
marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype …
marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype …
Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19
JYJ Tan, DE Anderson, APS Rathore… - The Journal of …, 2023 - Am Soc Clin Investig
Lung inflammation is a hallmark of Coronavirus disease 2019 (COVID-19) in patients who
are severely ill, and the pathophysiology of disease is thought to be immune mediated. Mast …
are severely ill, and the pathophysiology of disease is thought to be immune mediated. Mast …
[HTML][HTML] Gender differences in autoimmune disease
Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …
Mast cell secretory granules: armed for battle
S Wernersson, G Pejler - Nature Reviews Immunology, 2014 - nature.com
Mast cells are important effector cells of the immune system and recent studies show that
they have immunomodulatory roles in diverse processes in both health and disease. Mast …
they have immunomodulatory roles in diverse processes in both health and disease. Mast …
Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-Siglec-8 antibody
S Gebremeskel, J Schanin, KM Coyle… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection represents a
global health crisis. Immune cell activation via pattern recognition receptors has been …
global health crisis. Immune cell activation via pattern recognition receptors has been …
Roles of Mas-related G protein–coupled receptor X2 on mast cell–mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases
Mast cells (MCs), which are granulated tissue-resident cells of hematopoietic lineage,
contribute to vascular homeostasis, innate/adaptive immunity, and wound healing. However …
contribute to vascular homeostasis, innate/adaptive immunity, and wound healing. However …
Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE
Mast cells (MCs) are central effector cells in allergic reactions that are often mediated by
immunoglobulin E (IgE). Allergies commonly start at an early age, and both MCs and IgE are …
immunoglobulin E (IgE). Allergies commonly start at an early age, and both MCs and IgE are …
Mast cells signal their importance in health and disease
A Olivera, MA Beaven, DD Metcalfe - Journal of Allergy and Clinical …, 2018 - Elsevier
FcεRI is the primary receptor in mast cells that mediates allergic reactions by inducing rapid
release of mediators, an adaptive immune response that might have evolved as a host …
release of mediators, an adaptive immune response that might have evolved as a host …
Human mast cell proteome reveals unique lineage, putative functions, and structural basis for cell ablation
Mast cells are rare tissue-resident cells of importance to human allergies. To understand the
structural basis of principle mast cell functions, we analyzed the proteome of primary human …
structural basis of principle mast cell functions, we analyzed the proteome of primary human …