The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Multitargeting by curcumin as revealed by molecular interaction studies

SC Gupta, S Prasad, JH Kim, S Patchva… - Natural product …, 2011 - pubs.rsc.org
Covering: up to early 2011 Curcumin (diferuloylmethane), the active ingredient in turmeric
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …

[HTML][HTML] Water-in-oil Pickering emulsions stabilized by an interfacial complex of water-insoluble polyphenol crystals and protein

M Zembyla, BS Murray, SJ Radford, A Sarkar - Journal of Colloid and …, 2019 - Elsevier
Long term stabilization of water-in-oil (W/O) emulsions remains a particularly challenging
problem in colloid science. Recent studies have shown that polyphenols act as Pickering …

[HTML][HTML] Bioactive effects of curcumin in human immunodeficiency virus infection along with the most effective isolation techniques and type of nanoformulations

M Butnariu, C Quispe, N Koirala, S Khadka… - International Journal …, 2022 - ncbi.nlm.nih.gov
Human immunodeficiency virus (HIV) is one of the leading causes of death worldwide, with
African countries being the worst affected by this deadly virus. Curcumin (CUR) is a …

Curcumin and its analogues: a potential natural compound against HIV infection and AIDS

S Prasad, AK Tyagi - Food & function, 2015 - pubs.rsc.org
No safe and effective cure currently exists for human immunodeficiency virus (HIV).
However, antiretroviral therapy can prolong the lives of HIV patients and lowers the …

Understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases

SA Mandel, T Amit, O Weinreb… - Journal of Alzheimer's …, 2011 - content.iospress.com
During the last century, the world population has shown a staggering increase in its
proportion of elderly members and thus, neurodegenerative diseases like Alzheimer's and …

Polyphenol compounds and PKC signaling

J Das, R Ramani, MO Suraju - … et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Background Naturally occurring polyphenols found in food sources provide huge health
benefits. Several polyphenolic compounds are implicated in the prevention of disease …

Structure–activity relationship of curcumin: Role of the methoxy group in anti-inflammatory and anticolitis effects of curcumin

H Yang, Z Du, W Wang, M Song… - Journal of agricultural …, 2017 - ACS Publications
Curcumin, a dietary compound from turmeric, has beneficial effects on inflammatory
diseases such as inflammatory bowel disease. Most previous studies have focused on the …

C1 domains: structure and ligand-binding properties

J Das, GM Rahman - Chemical reviews, 2014 - ACS Publications
C1 domains are small zinc-binding structural units of approximately 50 amino acid residues,
originally discovered as lipid-binding modules in protein kinase C (PKC) isoforms. Although …

[HTML][HTML] Bioactivity of curcumin on the cytochrome P450 enzymes of the steroidogenic pathway

PR Castaño, S Parween, AV Pandey - International journal of molecular …, 2019 - mdpi.com
Turmeric, a popular ingredient in the cuisine of many Asian countries, comes from the roots
of the Curcuma longa and is known for its use in Chinese and Ayurvedic medicine. Turmeric …