Therapeutic hypothermia for mild neonatal encephalopathy: a systematic review and meta-analysis

U Kariholu, P Montaldo, T Markati, PJ Lally… - Archives of Disease in …, 2020 - fn.bmj.com
Objectives To examine if therapeutic hypothermia reduces the composite outcome of death,
moderate or severe disability at 18 months or more after mild neonatal encephalopathy …

Challenges in developing therapeutic strategies for mild neonatal encephalopathy

A McDouall, G Wassink, L Bennet… - Neural regeneration …, 2022 - journals.lww.com
There is increasing evidence that infants with mild neonatal encephalopathy (NE) have
significant risks of mortality, brain injury and adverse neurodevelopmental outcomes. In the …

[HTML][HTML] APGAR score

LV Simon, MF Hashmi, BN Bragg - 2017 - europepmc.org
Objectives: Identify the physiological criteria used for calculating the Apgar score. Describe
the clinical relevance of the Apgar score. Outline the limitations of the Apgar score. Explain …

Trends in the incidence and management of hypoxic-ischaemic encephalopathy in the therapeutic hypothermia era: a national population study

L Shipley, C Gale, D Sharkey - Archives of Disease in Childhood-Fetal …, 2021 - fn.bmj.com
Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

Mild hypoxic-ischemic encephalopathy (HIE): timing and pattern of MRI brain injury

Y Li, JL Wisnowski, L Chalak, AM Mathur… - Pediatric …, 2022 - nature.com
Background Mild hypoxic-ischemic encephalopathy (HIE) is increasingly recognized as a
risk factor for neonatal brain injury. We examined the timing and pattern of brain injury in …

Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway

T Chen, Y Hu, L Lu, Q Zhao, X Tao, B Ding… - Frontiers in …, 2023 - frontiersin.org
Introduction: Hypoxic-ischemic encephalopathy (HIE) is a crucial cause of neonatal death
and neurological sequelae, but currently there is no effective therapy drug for HIE. Both …

Predictive models of neurodevelopmental outcomes after neonatal hypoxic-ischemic encephalopathy

ES Peeples, R Rao, MLV Dizon, YR Johnson… - …, 2021 - publications.aap.org
OBJECTIVES: To develop predictive models for death or neurodevelopmental impairment
(NDI) after neonatal hypoxic-ischemic encephalopathy (HIE) from data readily available at …

Proposing a care practice bundle for neonatal encephalopathy during therapeutic hypothermia

P Wintermark, K Mohammad, SL Bonifacio - Seminars in Fetal and …, 2021 - Elsevier
Neonates with neonatal encephalopathy (NE) often present with multi-organ dysfunction that
requires multidisciplinary specialized management. Care of the neonate with NE is thus …

Utilization of therapeutic hypothermia and neurological injury in neonates with mild hypoxic-ischemic encephalopathy: a report from children's hospital neonatal …

R Rao, U Mietzsch, R DiGeronimo… - American journal of …, 2020 - thieme-connect.com
Objective This study was aimed to describe utilization of therapeutic hypothermia (TH) in
neonates presenting with mild hypoxic-ischemic encephalopathy (HIE) and associated …

Early blood glucose level post-admission correlates with the outcomes and oxidative stress in neonatal hypoxic-ischemic encephalopathy

IC Lee, JJ Yang, YM Liou - Antioxidants, 2021 - mdpi.com
The antioxidant defense system is involved in the pathogenesis of neonatal hypoxic-
ischemic encephalopathy (HIE). To analyze the relationship between first serum blood …