Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor

MS Denison, AA Soshilov, G He… - Toxicological …, 2011 - academic.oup.com
Abstract The Ah receptor (AhR) is a ligand-dependent transcription factor that mediates a
wide range of biological and toxicological effects that result from exposure to a structurally …

[HTML][HTML] The proteome and metabolome changes distinguish the effect of dietary energy levels on the development of ovary in chicken during sexual maturity

L Yin, X Wang, D Zhang, Z Lin, Y Wang, C Yu, H Jie… - Poultry Science, 2024 - Elsevier
To deeply understanding the impact of peripheral energy level on the development of
ovaries during the sexual maturation of chicken, in this study, the ovaries and serum of …

p23 co-chaperone protects the aryl hydrocarbon receptor from degradation in mouse and human cell lines

PM Nguyen, D Wang, Y Wang, Y Li, JA Uchizono… - Biochemical …, 2012 - Elsevier
The aryl hydrocarbon receptor (AhR) is a ligand-sensitive transcription factor which is
responsible for most 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin toxicities. Without ligand, the AhR …

Differential suppression of the aryl hydrocarbon receptor nuclear translocator-dependent function by an aryl hydrocarbon receptor PAS-A-derived inhibitory molecule

J Xie, X Huang, MS Park, HM Pham… - Biochemical pharmacology, 2014 - Elsevier
The aryl hydrocarbon receptor (AhR) heterodimerizes with the aryl hydrocarbon receptor
nuclear translocator (Arnt) for transcriptional regulation. We generated three N-terminal …

Suppression of the hypoxia inducible factor-1 function by redistributing the aryl hydrocarbon receptor nuclear translocator from nucleus to cytoplasm

Y Wang, Y Li, D Wang, Y Li, A Chang, WK Chan - Cancer letters, 2012 - Elsevier
The aryl hydrocarbon receptor nuclear translocator (ARNT) heterodimerizes with hypoxia
inducible factor-1α (HIF-1α), followed by upregulation of genes that are essential for …

Nuclear estrogen receptors co-activation mechanisms

M Skrzypczak, L Kapka-Skrzypczak… - Current Medicinal …, 2013 - ingentaconnect.com
Estrogens play very important role in opening the transcription event, which is a final step of
activation of the first order mediators as receptors or channels in the cell wall by information …

Study of the aryl hydrocarbon receptor as a target for rational drug design

J Xie - 2014 - search.proquest.com
The aryl hydrocarbon receptor (AhR) heterodimerizes with the aryl hydrocarbon receptor
nuclear translocator (Arnt) for transcriptional regulation. We generated three N-terminal …