Chemoprevention refers to the use of agents to inhibit, reverse or retard tumorigenesis.
Numerous phytochemicals derived from edible plants have been reported to interfere with a …

Curcumin, a component of turmeric (Curcuma longa), has been shown to exhibit
chemopreventive activity. Whether analogs of curcumin (Cur), such as demethoxycurcumin …

Abstract Resveratrol (trans-3, 4′, 5-trihydroxystilbene), a polyphenolic phytoalexin found in
grapes, fruits, and root extracts of the weed Polygonum cuspidatum, exhibits anti …

Tumour necrosis factor-α (TNFα) is a multifunctional cytokine belonging to a family of ligands
with an associated family of receptor proteins. The pleiotropic actions of TNF range from …

The process of tumorigenesis requires cellular transformation, hyperproliferation, invasion,
angiogenesis, and metastasis. Several genes that mediate these processes are regulated …

Abbreviations: Apaf, apoptosis protease activation factor; CAD, caspase-activated DNAse;
caspase, cysteine aspartate-directed protease; CAPK, ceramide-activated protein kinase; …

Asthma and chronic obstructive pulmonary disease are inflammatory lung disorders
responsible for significant morbidity and mortality worldwide. While the importance of …

The CXC chemokine, CXCL1 (melanoma growth-stimulatory activity/growth-regulated
protein α), plays a major role in inflammation, angiogenesis, tumorigenesis, and wound …

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin have been shown to
suppress transcription factor NF-κB, which controls the expression of genes such as …

Celastrol, a quinone methide triterpene derived from the medicinal plant Tripterygium
wilfordii, has been used to treat chronic inflammatory and autoimmune diseases, but its …