Role of Histone Deacetylases in the Pathogenesis of Salivary Gland Tumors and Therapeutic Targeting Options

M Manou, DS Kanakoglou, T Loupis… - International Journal of …, 2023 - mdpi.com
Salivary gland tumors (SGTs) comprise a rare and heterogenous category of
benign/malignant neoplasms with progressively increasing knowledge of the molecular …

Insights into the molecular alterations of PLAG1 and HMGA2 associated with malignant phenotype acquisition in pleomorphic adenoma

RA de Lima-Souza, G de Souza Vieira… - Critical Reviews in …, 2024 - Elsevier
Pleomorphic adenoma (PA) is the most common neoplasm of the salivary gland, presenting
with a variety of histological features. In some cases, PA can undergo malignant …

Molecular testing of cytology specimens: overview of assay selection with focus on lung, salivary gland, and thyroid testing

PA VanderLaan, S Roy-Chowdhuri, CC Griffith… - Journal of the American …, 2022 - Elsevier
Highlights•In this review article, we provide practical information for cytopathologists with
regard to molecular testing in general as well as specifically discuss recent molecular …

Cystic salivary gland neoplasms: diagnostic approach with a focus on ancillary studies

EA Ribeiro, Z Maleki - Advances in anatomic pathology, 2022 - journals.lww.com
Cystic salivary gland cytology can be challenging due to the fact that a cystic mass can be
the clinical presentation of both non-neoplastic and neoplastic conditions. Neoplastic …

Distinct copy number signatures between residual benign and transformed areas of carcinoma ex pleomorphic adenoma

JF Scarini, WL Sabino, RA de Lima-Souza… - Scientific Reports, 2024 - nature.com
The mechanisms involved with the pathogenesis of carcinoma ex pleomorphic adenoma
(CXPA) seem to be associated with the accumulation of molecular alterations in the …

Pitfalls in Diagnosis of Myoepithelial Carcinoma of Salivary Glands: A Study of 3 Cases with Cytologic-histologic Correlation and Molecular Analysis

S Agarwal - Head and Neck Pathology, 2024 - Springer
Design A database search for MECA was performed spanning 10 years. 3 cases qualified
with available cyto-histologic correlation. All were morphologically MECA with one case …

MAML2‐Rearranged Mucoepidermoid Carcinoma of the Parotid Gland: A Report in a 20‐Month‐Old Toddler

AA Owosho, AS Olatunji, AF Adejobi… - Case Reports in …, 2022 - Wiley Online Library
Malignancies of salivary gland origin are rare in children. Mucoepidermoid carcinoma
(MEC) is the most common histologic type of salivary gland neoplasm in pediatrics. We …