Metallodrugs in medicinal inorganic chemistry

KD Mjos, C Orvig - Chemical reviews, 2014 - ACS Publications
Metal ions play important roles in biological processes, 1 and the field of knowledge
concerned with the application of inorganic chemistry to therapy or diagnosis of disease is …

New world and old world Leishmania infections: a practical review

I Kevric, MA Cappel, JH Keeling - Dermatologic clinics, 2015 - derm.theclinics.com
Leishmaniasis is a tropical disease caused by an intracellular parasite of the genus
Leishmania. The vector of transmission is the sandfly, which deposits one of the 20 disease …

Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical …

N Aronson, BL Herwaldt, M Libman… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that leishmaniasis guidelines cannot always account for individual
variation among patients. They are not intended to supplant physician judgment with respect …

Recent development of visceral leishmaniasis treatments: successes, pitfalls, and perspectives

F Alves, G Bilbe, S Blesson, V Goyal… - Clinical microbiology …, 2018 - Am Soc Microbiol
Research in visceral leishmaniasis in the last decade has been focused on how better to
use the existing medicines as monotherapy or in combination. Systematic research by …

Cutaneous leishmaniasis

R Reithinger, JC Dujardin, H Louzir… - The Lancet infectious …, 2007 - thelancet.com
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a
group of diseases because of the varied spectrum of clinical manifestations, which range …

Chemotherapy of leishmaniasis: present challenges

SRB Uliana, CT Trinconi, AC Coelho - Parasitology, 2018 - cambridge.org
Cutaneous and visceral leishmaniasis are amongst the most devastating infectious diseases
of our time, affecting millions of people worldwide. The treatment of these serious diseases …

The relationship between leishmaniasis and AIDS: the second 10 years

J Alvar, P Aparicio, A Aseffa, M Den Boer… - Clinical microbiology …, 2008 - Am Soc Microbiol
To date, most Leishmania and human immunodeficiency virus (HIV) coinfection cases
reported to WHO come from Southern Europe. Up to the year 2001, nearly 2,000 cases of …

Kinetoplastids: related protozoan pathogens, different diseases

K Stuart, R Brun, S Croft, A Fairlamb… - The Journal of …, 2008 - Am Soc Clin Investig
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma
and Leishmania, which are human pathogens with devastating health and economic effects …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial

S Sundar, PK Sinha, M Rai, DK Verma, K Nawin… - The Lancet, 2011 - thelancet.com
Background Improved treatment approaches are needed for visceral leishmaniasis. We
assessed the efficacy and safety of three potential short-course combination treatments …