The phenomenon of multidrug resistance (MDR) in cancer is associated with the
overexpression of the ATP-binding cassette (ABC) transporter proteins, including multidrug …

Maslinic acid is a pentacyclic triterpene found in a variety of natural sources, ranging from
herbal remedies used in traditional Asian medicine to edible vegetables and fruits present in …

Multidrug resistance (MDR) in cancer is one of the main limitations for chemotherapy
success. Numerous mechanisms are behind the MDR phenomenon wherein the …

Oleanane and ursane pentacyclic triterpenoids are secondary metabolites of plants found in
various climatic zones and regions. This group of compounds is highly attractive due to their …

The role of intestinal barrier homeostasis in an individual's general well-being has been
widely addressed by the scientific community. Colorectal cancer is among the illnesses that …

Cancer is still an insurmountable problem for humans and critically attacking human health.
In recent years, natural products have gained increasing attention in the field of anti-tumor …

Background/Aims: P-glycoprotein (P-gp, ie, MDR1) is associated with the phenotype of
multidrug resistance (MDR) and causes chemotherapy failure in the management of …

Maslinic acid has a variety of biological activities, such as anti‐tumor, hypoglycemic, anti‐
inflammatory, and anti‐parasitic. In order to enhance the biological activity of maslinic acid …

Maslinic acid is a pentacyclic triterpene extracted from olives that has been systematically
reported to exert several therapeutic effects, such as antitumoral, antidiabetic, antioxidant …

Ursolic, oleanolic and betulinic acids are representative pentacyclic triterpenoids found in
various plants and fruits. Despite having marked antitumor potentials, the very poor water …