In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications
A Pałasz, D Cież - European journal of medicinal chemistry, 2015 - Elsevier
This review article is an effort to summarize recent developments in researches providing
uracil derivatives with promising biological potential. This article also aims to discuss …
uracil derivatives with promising biological potential. This article also aims to discuss …
Thieno [2, 3-d] pyrimidine as a promising scaffold in medicinal chemistry: Recent advances
EMH Ali, MS Abdel-Maksoud, CH Oh - Bioorganic & medicinal chemistry, 2019 - Elsevier
Thienopyrimidine scaffold is a fused heterocyclic ring system that structurally can be
considered as adenine, the purine base that is found in both DNA and RNA-bioisosteres …
considered as adenine, the purine base that is found in both DNA and RNA-bioisosteres …
[PDF][PDF] Design, synthesis and antimicrobial screening of some new thienopyrimidines
Heterocyclic compounds play an important role in our life due to their biological importance
in the struggle of microorganisms. Herein, a series of novel hybrid compounds of …
in the struggle of microorganisms. Herein, a series of novel hybrid compounds of …
Synthesis and biological evaluation of thieno [2′, 3′: 4, 5] pyrimido [1, 2-b][1, 2, 4] triazines and thieno [2, 3-d][1, 2, 4] triazolo [1, 5-a] pyrimidines as anti …
A new series of thieno [2′, 3′: 4, 5] pyrimido [1, 2-b][1, 2, 4] triazines and thieno [2, 3-d][1,
2, 4] triazolo [1, 5-a] pyrimidines was synthesized. The newly synthesized compounds were …
2, 4] triazolo [1, 5-a] pyrimidines was synthesized. The newly synthesized compounds were …
Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro …
A multicomponent synthesis was empolyed for the synthesis of ethyl 2-amino-4, 5, 6, 7-
tetrahydrobenzo [b] thiophene-3-carboxylate 1. An interesting cyclization was obtained …
tetrahydrobenzo [b] thiophene-3-carboxylate 1. An interesting cyclization was obtained …
Synthesis and in vitro antitumor evaluation of some new thiophenes and thieno [2, 3-d] pyrimidine derivatives
MM Fouad, ER El-Bendary, IA Shehata… - Bioorganic …, 2018 - Elsevier
Abstract New thiophene (2–13) and thienopyrimidine (15–27) derivatives have been
synthesized. Twenty three compounds were screened against five cell lines namely; …
synthesized. Twenty three compounds were screened against five cell lines namely; …
Design and synthesis of novel indole derivatives with aggregation-induced emission and antimicrobial activity
New heterocyclic compounds containing indolylthienopyrimidine have been synthesized
and their structures were confirmed using elemental and spectral analyses. The …
and their structures were confirmed using elemental and spectral analyses. The …
[PDF][PDF] Combined 3D-QSAR and molecular docking analysis of thienopyrimidine derivatives as Staphylococcus aureus inhibitors
The discovery of antibacterials is considered one of the greatest medical achievements of all
time. In this work, a combination of three computational analyzes: 3D-QSAR, molecular …
time. In this work, a combination of three computational analyzes: 3D-QSAR, molecular …
Thiophene derivatives: A potent multitargeted pharmacological scaffold
Despite a significant work that has been done on thiophene, continuous efforts are still being
made by the researchers to identify novel heterocyclic compounds with potential …
made by the researchers to identify novel heterocyclic compounds with potential …
Novel thiophene derivatives with sulfonamide, isoxazole, benzothiazole, quinoline and anthracene moieties as potential anticancer agents
MM Ghorab, MS Bashandy, MS AL-SAID - Acta Pharmaceutica, 2014 - hrcak.srce.hr
Sažetak A novel series of thiophenes having biologically active sulfonamide (2-11), 3-
methylisoxazole (12), 4-methoxybenzo [d] thiazole (13), quinoline (14, 15) …
methylisoxazole (12), 4-methoxybenzo [d] thiazole (13), quinoline (14, 15) …