Genetic decoding is not 'frozen'as was earlier thought, but dynamic. One facet of this is
frameshifting that often results in synthesis of a C-terminal region encoded by a new frame …

Transfer RNA's role in decoding the genome is critical to the accuracy and efficiency of
protein synthesis. Though modified nucleosides were identified in RNA 50 years ago, only …

We replaced degenerate codons for nine amino acids within the capsid region of the Sabin
type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons …

Aminoacylated (charged) transfer RNA isoacceptors read different messenger RNA codons
for the same amino acid. The concentration of an isoacceptor and its charged fraction are …

This highly illustrated book provides an up-to-date description of the structure and function of
the translation system including ribosomes, tRNAs, translation factors, antibiotics and …

Background Elephants are classified as critically endangered animals by the International
Union for Conservation of Species (IUCN). Elephant endotheliotropic herpesvirus (EEHV) …

Summary The Shine–Dalgarno (SD+: 5′‐AAGGAGG‐3′) sequence anchors the mRNA by
base pairing to the 16S rRNA in the small ribosomal subunit during translation initiation. We …

During mRNA translation, synonymous codons for one amino acid are often read by different
isoaccepting tRNAs. The theory of selective tRNA charging predicts greatly varying …

In Streptomyces species, the cell cycle involves a switch from an early and vegetative state
to a later phase where secondary products including antibiotics are synthesized, aerial …

The transcriptome provides a functional footprint of the genome by enumerating the
molecular components of cells and tissues. The field of transcript discovery has been …