Highlights•Reward Prediction Error (RPE) remains a compelling theory accounting for VTA dopamine neuron activity•RPE theory now incorporates sensory prediction errors …
Significant evidence supports the view that dopamine shapes learning by encoding reward prediction errors. However, it is unknown whether striatal targets receive tailored dopamine …
Rapid phasic activity of midbrain dopamine neurons is thought to signal reward prediction errors (RPEs), resembling temporal difference errors used in machine learning. However …
Hippocampal place cells support reward-related spatial memories by forming a cognitive map that over-represents reward locations. The strength of these memories is modulated by …
Dopamine contributes to cognitive control through well-established effects in both the striatum and cortex. Although earlier work suggests that dopamine affects cognitive control …
Animals frequently make decisions based on expectations of future reward (" values"). Values are updated by ongoing experience: places and choices that result in reward are …
AE Hamilos, G Spedicato, Y Hong, F Sun, Y Li… - Elife, 2021 - elifesciences.org
Clues from human movement disorders have long suggested that the neurotransmitter dopamine plays a role in motor control, but how the endogenous dopaminergic system …
Goal-directed navigation requires learning to accurately estimate location and select optimal actions in each location. Midbrain dopamine neurons are involved in reward value learning …
Optimal behavior requires interpreting environmental cues that indicate when to perform actions. Dopamine is important for learning about reward-predicting events, but its role in …