The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

The H-NOX protein structure adapts to different mechanisms in sensors interacting with nitric oxide

BK Yoo, SG Kruglik, JC Lambry, I Lamarre… - Chemical …, 2023 - pubs.rsc.org
Some classes of bacteria within phyla possess protein sensors identified as homologous to
the heme domain of soluble guanylate cyclase, the mammalian NO-receptor. Named H-NOX …

Repurposing a Nitric Oxide Transport Hemoprotein Nitrophorin 2 for Olefin Cyclopropanation

S Huang, WH Deng, RZ Liao, C He - ACS Catalysis, 2022 - ACS Publications
A growing number of heme proteins have recently been repurposed for catalyzing
abiological carbene transfer reactions. Herein, we rationally designed an engineered variant …

Cytochrome P460 Cofactor Maturation Proceeds via Peroxide-Dependent Post-translational Modification

MM Bollmeyer, RE Coleman, SH Majer… - Journal of the …, 2023 - ACS Publications
Cytochrome P460s are heme enzymes that oxidize hydroxylamine to nitrous oxide. They
bear specialized “heme P460” cofactors that are cross-linked to their host polypeptides by a …

Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and Quantum Mechanics and Molecular Mechanics Theoretical Investigations of Preferred FeNO …

B Wang, Y Shi, J Tejero, SM Powell, LM Thomas… - Biochemistry, 2018 - ACS Publications
The globular dioxygen binding heme protein myoglobin (Mb) is present in several species.
Its interactions with the simple nitrogen oxides, namely, nitric oxide (NO) and nitrite, have …

Interaction of nitrite with ferric protoglobin from Methanosarcina acetivorans–an interesting model for spectroscopic studies of the haem–ligand interaction

R Sgammato, N Van Brempt, R Aerts… - Dalton …, 2023 - pubs.rsc.org
Protoglobin from Methanosarcina acetivorans (MaPgb) is a dimeric globin belonging to the
same lineage of the globin superfamily as globin-coupled sensors. A putative role in the …

The Heme–Lys Cross-Link in Cytochrome P460 Promotes Catalysis by Enforcing Secondary Coordination Sphere Architecture

RE Coleman, AC Vilbert, KM Lancaster - Biochemistry, 2020 - ACS Publications
Cytochrome (cyt) P460 is ac-type monoheme enzyme found in ammonia-oxidizing bacteria
(AOB) and methanotrophs; additionally, genes encoding it have been found in some …

Impact of the dynamics of the catalytic arginine on nitrite and chlorite binding by dimeric chlorite dismutase

I Serra, D Schmidt, V Pfanzagl, G Mlynek… - Journal of Inorganic …, 2022 - Elsevier
Chlorite dismutases (Clds) are heme b containing oxidoreductases able to decompose
chlorite to chloride and molecular oxygen. This work analyses the impact of the distal …

The effect of pH and nitrite on the haem pocket of GLB-33, a globin-coupled neuronal transmembrane receptor of Caenorhabditis elegans

N Van Brempt, R Sgammato, Q Beirinckx… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Out of the 34 globins in Caenorhabditis elegans, GLB-33 is a putative globin-coupled
transmembrane receptor with a yet unknown function. The globin domain (GD) contains a …

[HTML][HTML] Nitrosyl Myoglobins and Their Nitrite Precursors: Crystal Structural and QM/MM Theoretical Investigations into Preferred Fe–NO Ligand Orientations in …

B Wang, Y Shi, J Tejero, SM Powell, LM Thomas… - Biochemistry, 2018 - ncbi.nlm.nih.gov
The globular dioxygen-binding heme protein myoglobin (Mb) is present in several species.
Its interactions with the simple nitrogen oxides, namely nitric oxide (NO) and nitrite, have …