Targeting and engineering long non-coding RNAs for cancer therapy
RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …
Role of genomics in combating COVID-19 pandemic
Abstract The coronavirus disease 2019 (COVID-19) quickly swept over the world, becoming
one of the most devastating outbreaks in human history. Being the first pandemic in the post …
one of the most devastating outbreaks in human history. Being the first pandemic in the post …
Silencing of SARS‐CoV‐2 with modified siRNA‐peptide dendrimer formulation
Background First vaccines for prevention of Coronavirus disease 2019 (COVID‐19) are
becoming available but there is a huge and unmet need for specific forms of treatment. In …
becoming available but there is a huge and unmet need for specific forms of treatment. In …
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread
A promising approach to tackle the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …
[HTML][HTML] Diagnostic assay and technology advancement for detecting SARS-CoV-2 infections causing the COVID-19 pandemic
BC Dhar - Analytical and Bioanalytical Chemistry, 2022 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-caused COVID-19
pandemic has transmitted to humans in practically all parts of the world, producing socio …
pandemic has transmitted to humans in practically all parts of the world, producing socio …
Targeting the conserved stem loop 2 motif in the SARS-CoV-2 genome
ABSTRACT RNA structural elements occur in numerous single-stranded positive-sense
RNA viruses. The stem-loop 2 motif (s2m) is one such element with an unusually high …
RNA viruses. The stem-loop 2 motif (s2m) is one such element with an unusually high …
[HTML][HTML] Development and application of ribonucleic acid therapy strategies against COVID-19
L Ning, M Liu, Y Gou, Y Yang, B He… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract The Coronavirus disease 2019 (COVID-19) pandemic is caused by the severe
acute respiratory syndrome 2 coronavirus (SARS-CoV-2), remaining a global health crisis …
acute respiratory syndrome 2 coronavirus (SARS-CoV-2), remaining a global health crisis …
A review on advanced CRISPR-based genome-editing tools: base editing and prime editing
A Saber Sichani, M Ranjbar, M Baneshi… - Molecular …, 2023 - Springer
In the field of medicine, it is axiomatic that the need of a precise gene-editing tool is critical to
employ therapeutic approaches toward pathogenic mutations, occurring in human genome …
employ therapeutic approaches toward pathogenic mutations, occurring in human genome …
[HTML][HTML] Inhibition of SARS-CoV-2 by targeting conserved viral RNA structures and sequences
The ongoing COVID-19/Severe Acute Respiratory Syndrome CoV-2 (SARS-CoV-2)
pandemic has become a significant threat to public health and has hugely impacted …
pandemic has become a significant threat to public health and has hugely impacted …
RNA in cancer immunotherapy: unlocking the potential of the immune system
W De Mey, A Esprit, K Thielemans, K Breckpot… - Clinical Cancer …, 2022 - AACR
Recent advances in the manufacturing, modification, purification, and cellular delivery of
ribonucleic acid (RNA) have enabled the development of RNA-based therapeutics for a …
ribonucleic acid (RNA) have enabled the development of RNA-based therapeutics for a …