The dissemination of tumor cells to local and distant sites presents a significant challenge in
the clinical management of many solid tumors. These cells may remain dormant for months …

Abstract N6-methyladenosine (m6A) is the most abundant posttranscriptional modification of
mRNA in eukaryotes. Recent evidence suggests that dysregulated m6A-associated proteins …

Abstract Background The lncRNA LINC00460 plays crucial roles in several epithelial
cancers, although its mechanisms of action differ greatly in different cellular contexts. In this …

Laryngeal squamous cell carcinoma (LSCC) is a common form of head and neck cancer
with poor prognosis. However, the mechanism underlying the pathogenesis of LSCC …

Lung adenocarcinoma (LUAD) is a common type of lung cancer with high frequent
metastasis and a high death rate. However, genes responsible for LUAD metastasis are still …

The RAL proteins RALA and RALB belong to the superfamily of small RAS-like GTPases
(guanosine triphosphatases). RAL GTPases function as molecular switches in cells by …

Increasing studies showed that kinesin family member 20A (KIF20A) was overexpessed in
several types of cancer, and its overexpression correlated with the oncogenesis and …

The low survival rate of esophageal squamous cell carcinoma patients is primarily attributed
to technical limitations and a lack of insight regarding the molecular mechanisms …

Objective To clarify the modulatory mechanism of miR-31-5p in lung adenocarcinoma
(LUAD) progression in vivo and in vitro. Methods The Cancer Genome Atlas (TCGA) …

Weighted gene co-expression network analysis (WGCNA) identified a cell-cycle module that
is associated with poor prognosis and aggressiveness of glioma. One of the core members …