The human mast cell: an overview

G Krishnaswamy, O Ajitawi, DS Chi - Mast Cells: Methods and Protocols, 2005 - Springer
Mast cells are fascinating, multifunctional, tissue-dwelling cells that have been traditionally
associated with the allergic response. However, recent studies suggest these cells may be …

The human mast cell

G Krishnaswamy, O Ajitawi, DS Chi - Mast Cells, 2001 - Springer
Mast cells are fascinating, multifunctional, tissue-dwelling cells that have been traditionally
associated with the allergic response. However, recent studies suggest these cells may be …

Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia

EA Garcia-Zepeda, ME Rothenberg, RT Ownbey… - Nature medicine, 1996 - nature.com
Eotaxin is an eosinophil–specific chemoattractant that has been recently identified in rodent
models of asthma and host response against tumors. To determine whether a similar …

IL-4 enhances proliferation and mediator release in mature human mast cells

SC Bischoff, G Sellge, A Lorentz… - Proceedings of the …, 1999 - National Acad Sciences
Tissue mast cells (MC) are recognized as key effector cells of immediate-type allergic
reactions releasing inflammatory mediators and cytokines on stimulation with antigen, but …

Nitric oxide: a regulator of mast cell activation and mast cell-mediated inflammation

JW Coleman - Clinical & Experimental Immunology, 2002 - academic.oup.com
Nitric oxide (NO) plays diverse roles in physiological and pathological processes. During
immune and inflammatory responses, for example in asthma, NO is generated at relatively …

Human intestinal mast cells are capable of producing different cytokine profiles: role of IgE receptor cross-linking and IL-4

A Lorentz, S Schwengberg, G Sellge… - The Journal of …, 2000 - journals.aai.org
Mast cells are recognized as a new type of immunoregulatory cells capable of producing
different cytokines. So far, little is known about the cytokine profile of mature human mast …

Cytokine production by skin-derived mast cells: endogenous proteases are responsible for degradation of cytokines

W Zhao, CA Oskeritzian, AL Pozez… - The Journal of …, 2005 - journals.aai.org
The current study characterizes the cytokine protein (ELISA) and mRNA (gene array and RT-
PCR) profiles of skin-derived mast cells cultured under serum-free conditions when …

[HTML][HTML] Effects of G-Rh2 on mast cell-mediated anaphylaxis via AKT-Nrf2/NF-κB and MAPK-Nrf2/NF-κB pathways

C Xu, L Li, C Wang, J Jiang, L Li, L Zhu, S Jin… - Journal of Ginseng …, 2022 - Elsevier
Background The effect of ginsenoside Rh2 (G-Rh2) on mast cell-mediated anaphylaxis
remains unclear. Herein, we investigated the effects of G-Rh2 on OVA-induced asthmatic …

Induced expression of mRNA for IL-5, IL-6, TNF-alpha, MIP-2 and IFN-gamma in immunologically activated rat peritoneal mast cells: inhibition by dexamethasone and …

CM Williams, JW Coleman - Immunology, 1995 - ncbi.nlm.nih.gov
We examined the capacity of purified rat peritoneal connective tissue-type mast cells (PMC)
to express mRNA for several cytokines. Stimulation of PMC with anti-IgE for 4 hr induced the …

Human mast cells transmigrate through human umbilical vein endothelial monolayers and selectively produce IL-8 in response to stromal cell-derived factor-1α

TJ Lin, TB Issekutz, JS Marshall - The Journal of Immunology, 2000 - journals.aai.org
Mature mast cells are generally considered to be less mobile cells residing within tissue
sites. However, mast cell numbers are known to increase in the context of inflammation, and …