N Ozber, JL Watkins, PJ Facchini - Journal of Industrial …, 2020 - academic.oup.com
Microbial fermentation platforms offer a cost-effective and sustainable alternative to plant cultivation and chemical synthesis for the production of many plant-derived pharmaceuticals …
J Cao, B Yang, M Zhang, F Yu - Biotechnology letters, 2024 - Springer
To investigate the effect of subcellular localization on the transformation efficiency of heterologous expressed functional P450s in yeast. Microbial biotransformation offers a …
A Berger, K Valant-Vetschera, J Schinnerl… - Phytochemistry …, 2022 - Springer
The species-rich genus Palicourea (Rubiaceae: Palicoureeae) is source of an intriguing diversity of alkaloids derived from tryptamine and its precursor tryptophan. So far simple …
Biosynthesis of the therapeutically valuable terpenoid indole alkaloids (TIAs), in the medicinal plant Catharanthus roseus, is one of the most elaborate and complex metabolic …
Elucidation of biological pathways leading to specialized metabolites remains a complex task. It is however a mandatory step to allow bioproduction into heterologous hosts. Many …
TAM Nguyen, M McConnachie, TD Nguyen… - … roseus: Methods and …, 2022 - Springer
Monoterpene indole alkaloid (MIA) constitutes a structurally diverse plant natural product group with remarkable pharmacological activities. Many MIAs have been routinely used as …
The plant Catharanthus roseus is well known for its spatial separation of iridoid and monoterpenoid indole alkaloid (MIA) biosynthesis at both intracellular and intercellular …
I Carqueijeiro, LJ Sepúlveda, A Mosquera… - … Trafficking: Methods and …, 2018 - Springer
Accurate and efficient demonstrations of protein localizations to the vacuole or tonoplast remain strict prerequisites to decipher the role of vacuoles in the whole plant cell biology …