Comprehensive overview of glucosinolates in crucifers: Occurrence, roles, metabolism, and transport mechanisms—A review

S Sharma, H Rani, G Kaur, S Kumar, S Sheikh… - Phytochemistry …, 2024 - Springer
Plants of the Brassicaceae family exhibit a sophisticated defense mechanism against plant
pathogens and insect herbivores, leading to the production of diverse hydrolytic derivatives …

Back to the plant: overcoming roadblocks to the microbial production of pharmaceutically important plant natural products

N Ozber, JL Watkins, PJ Facchini - Journal of Industrial …, 2020 - academic.oup.com
Microbial fermentation platforms offer a cost-effective and sustainable alternative to plant
cultivation and chemical synthesis for the production of many plant-derived pharmaceuticals …

Regulation of T16H subcellular localization for promoting its catalytic efficiency in yeast cells

J Cao, B Yang, M Zhang, F Yu - Biotechnology letters, 2024 - Springer
To investigate the effect of subcellular localization on the transformation efficiency of
heterologous expressed functional P450s in yeast. Microbial biotransformation offers a …

Alkaloid diversification in the genus Palicourea (Rubiaceae: Palicoureeae) viewed from a (retro-)biogenetic perspective

A Berger, K Valant-Vetschera, J Schinnerl… - Phytochemistry …, 2022 - Springer
The species-rich genus Palicourea (Rubiaceae: Palicoureeae) is source of an intriguing
diversity of alkaloids derived from tryptamine and its precursor tryptophan. So far simple …

Identification and Characterization of Transcription Factors Regulating Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

SK Singh, B Patra, JJ Singleton, Y Liu, P Paul… - … roseus: Methods and …, 2022 - Springer
Biosynthesis of the therapeutically valuable terpenoid indole alkaloids (TIAs), in the
medicinal plant Catharanthus roseus, is one of the most elaborate and complex metabolic …

Predicting monoterpene indole alkaloid-related genes from expression data with artificial neural networks

T Dugé de Bernonville, E Amor Stander… - … roseus: Methods and …, 2022 - Springer
Elucidation of biological pathways leading to specialized metabolites remains a complex
task. It is however a mandatory step to allow bioproduction into heterologous hosts. Many …

Discovery and characterization of oxidative enzymes involved in monoterpenoid indole alkaloid biosynthesis

TAM Nguyen, M McConnachie, TD Nguyen… - … roseus: Methods and …, 2022 - Springer
Monoterpene indole alkaloid (MIA) constitutes a structurally diverse plant natural product
group with remarkable pharmacological activities. Many MIAs have been routinely used as …

Studying Iridoid Transport in Catharanthus roseus by Grafting

M Farzana, M Shahsavarani, V De Luca… - … roseus: Methods and …, 2022 - Springer
The plant Catharanthus roseus is well known for its spatial separation of iridoid and
monoterpenoid indole alkaloid (MIA) biosynthesis at both intracellular and intercellular …

Vacuole-targeted proteins: ins and outs of subcellular localization studies

I Carqueijeiro, LJ Sepúlveda, A Mosquera… - … Trafficking: Methods and …, 2018 - Springer
Accurate and efficient demonstrations of protein localizations to the vacuole or tonoplast
remain strict prerequisites to decipher the role of vacuoles in the whole plant cell biology …