Machine learning in mental health: a scoping review of methods and applications
BackgroundThis paper aims to synthesise the literature on machine learning (ML) and big
data applications for mental health, highlighting current research and applications in …
data applications for mental health, highlighting current research and applications in …
The function and regulation of zinc in the brain
RF Krall, T Tzounopoulos, E Aizenman - Neuroscience, 2021 - Elsevier
Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …
rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …
Validity and utility of hierarchical taxonomy of psychopathology (HiTOP): I. Psychosis superspectrum
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …
Modeling gene× environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression
Post-traumatic stress disorder (PTSD) can develop following severe trauma, but the extent to
which genetic and environmental risk factors contribute to individual clinical outcomes is …
which genetic and environmental risk factors contribute to individual clinical outcomes is …
How to do quantile normalization correctly for gene expression data analyses
Quantile normalization is an important normalization technique commonly used in high-
dimensional data analysis. However, it is susceptible to class-effect proportion effects (the …
dimensional data analysis. However, it is susceptible to class-effect proportion effects (the …
Epigenomic dysregulation in schizophrenia: in search of disease etiology and biomarkers
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …
that causes very significant disability in young people. While schizophrenia has a strong …
Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data
Individuals with psychiatric disorders have elevated rates of autoimmune comorbidity and
altered immune signaling. It is unclear whether these altered immunological states have a …
altered immune signaling. It is unclear whether these altered immunological states have a …
Neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio and platelet-lymphocyte ratio in non-affective psychosis: a meta-analysis and systematic review
MG Mazza, S Lucchi, A Rossetti… - The World Journal of …, 2020 - Taylor & Francis
Objectives: Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and
monocyte/lymphocyte ratio (MLR) are inexpensive and reproducible biomarkers of …
monocyte/lymphocyte ratio (MLR) are inexpensive and reproducible biomarkers of …
Postmortem transcriptional profiling reveals widespread increase in inflammation in schizophrenia: a comparison of prefrontal cortex, striatum, and hippocampus …
TA Lanz, V Reinhart, MJ Sheehan, SJS Rizzo… - Translational …, 2019 - nature.com
Psychiatric disorders such as schizophrenia (SCZ), bipolar disorder (BD), and major
depressive disorder (MDD) arise from complex interactions between genetic and …
depressive disorder (MDD) arise from complex interactions between genetic and …
Microglia and brain plasticity in acute psychosis and schizophrenia illness course: a meta-review
Objective Schizophrenia poses a tremendous health, social, and economic burden upon
patients and society, indicating current treatment options remain inadequate. Recent …
patients and society, indicating current treatment options remain inadequate. Recent …