MRI assessment of cerebral perfusion in clinical trials
X Wang, C Bishop, J O'Callaghan, A Gayhoor… - Drug Discovery …, 2023 - Elsevier
Highlights•Use of MRI perfusion imaging in clinical trials and as an alternative to other
imaging modalities.•Detailed description of imaging procedures, best practices in clinical …
imaging modalities.•Detailed description of imaging procedures, best practices in clinical …
Recent advances in arterial spin labeling perfusion MRI in patients with vascular cognitive impairment
D Huang, Y Guo, X Guan, L Pan, Z Zhu… - Journal of Cerebral …, 2023 - journals.sagepub.com
Cognitive impairment (CI) is a major health concern in aging populations. It impairs patients'
independent life and may progress to dementia. Vascular cognitive impairment (VCI) …
independent life and may progress to dementia. Vascular cognitive impairment (VCI) …
Association of intensive vs standard blood pressure control with cerebral blood flow: secondary analysis of the SPRINT MIND randomized clinical trial
Importance Antihypertensive treatments benefit cerebrovascular health and cognitive
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …
[HTML][HTML] Arterial spin labeling versus 18F-FDG-PET to identify mild cognitive impairment
Neurodegenerative biomarkers support diagnosis and measurement of disease progression
in the Alzheimer's disease (AD) continuum. 18 F-Fluorodeoxyglucose Positron Emission …
in the Alzheimer's disease (AD) continuum. 18 F-Fluorodeoxyglucose Positron Emission …
Recommendations for quantitative cerebral perfusion MRI using multi‐timepoint arterial spin labeling: Acquisition, quantification, and clinical applications
Accurate assessment of cerebral perfusion is vital for understanding the hemodynamic
processes involved in various neurological disorders and guiding clinical decision‐making …
processes involved in various neurological disorders and guiding clinical decision‐making …
[HTML][HTML] Simultaneously acquired PET and ASL imaging biomarkers may be helpful in differentiating progression from pseudo-progression in treated gliomas
Objectives The aim of this work was investigating the methods based on coupling cerebral
perfusion (ASL) and amino acid metabolism ([18 F] DOPA-PET) measurements to evaluate …
perfusion (ASL) and amino acid metabolism ([18 F] DOPA-PET) measurements to evaluate …
[HTML][HTML] Detection of ictal and periictal hyperperfusion with subtraction of ictal-interictal 1.5-Tesla pulsed arterial spin labeling images co-registered to conventional …
K Abe, T Shimogawa, N Mukae, K Ikuta… - Surgical Neurology …, 2023 - ncbi.nlm.nih.gov
Background: Our recent report showed that 1.5-T pulsed arterial spin labeling (ASL)
magnetic resonance (MR) perfusion imaging (1.5-T Pulsed ASL [PASL]), which is widely …
magnetic resonance (MR) perfusion imaging (1.5-T Pulsed ASL [PASL]), which is widely …
Analysis of costs for imaging-assisted pharmaceutical intervention in Alzheimer's disease with lecanemab: Snapshot of the first 3 years
Background: The approval of lecanemab for the treatment of Alzheimer's disease (AD) by
the Food and Drug Administration in the United States has sparked controversy over issues …
the Food and Drug Administration in the United States has sparked controversy over issues …
Prospective longitudinal perfusion in probable Alzheimer's disease correlated with atrophy in temporal lobe
Reduced cerebral blood flow (CBF) in the temporoparietal region and gray matter volumes
(GMVs) in the temporal lobe were previously reported in patients with mild cognitive …
(GMVs) in the temporal lobe were previously reported in patients with mild cognitive …
Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia
Cerebral blood flow (CBF) measured with arterial spin labelling (ASL) magnetic resonance
imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time …
imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time …