Organophosphate pesticide-induced toxicity through DNA damage and DNA repair mechanisms

J Prathiksha, RK Narasimhamurthy, HS Dsouza… - Molecular Biology …, 2023 - Springer
Organophosphate pesticides (OPs) are widely used in agriculture, healthcare, and other
industries due to their ability to kill pests. However, OPs can also have genotoxic effects on …

Mechanisms of Neurotoxicity of Organophosphate Pesticides and Their Relation to Neurological Disorders

Y Chen, Z Yang, B Nian, C Yu, D Maimaiti… - Neuropsychiatric …, 2024 - Taylor & Francis
Organophosphates (OPs) refers to a diverse group of phosphorus-containing organic
compounds; they are widely used all over the world and have had an important beneficial …

[HTML][HTML] Residual levels and dietary exposure risk assessment of banned pesticides in fruits and vegetables from Chinese market based on long-term nontargeted …

S Liang, H Li, Q Chang, R Bai, Z Zhao… - … and Environmental Safety, 2022 - Elsevier
The negative impact of banned pesticides is of special importance for their high toxicity. In
this study, nationwide screening of banned pesticides in 37462 fruit and vegetable samples …

[HTML][HTML] MicroRNAs alteration as early biomarkers for cancer and neurodegenerative diseases: New challenges in pesticides exposure

C Costa, M Teodoro, CA Rugolo, C Alibrando… - Toxicology Reports, 2020 - Elsevier
This review summarizes the current knowledge linking cancer and neuro-degenerative
diseases to dysregulation of microRNA network following pesticide exposure. Most findings …

Occupational exposure to pesticides and its association with telomere length-A systematic review and meta-analysis

JDC Passos, K Felisbino, HA Laureano… - Science of The Total …, 2022 - Elsevier
Background Telomere length is a common biomarker for the cumulative effect of
environmental factors on aging-related diseases, therefore an association has been …

Dimethoate induces genotoxicity as a result of oxidative stress: In vivo and in vitro studies

MS Silva, DV De Souza, MES Alpire… - … Science and Pollution …, 2021 - Springer
Abstract Dimethoate ([O, O-dimethyl S-(N-methylcarbamoylmethyl) phosphorodithioate]) is
an organophosphate insecticide and acaricide widely used for agricultural purposes …

Effects of polycyclic aromatic hydrocarbon exposure and miRNA variations on peripheral blood leukocyte DNA telomere length: a cross-sectional study in Henan …

X Duan, D Zhang, S Wang, X Feng, T Wang… - Science of the Total …, 2020 - Elsevier
Telomeres play a major role in human aging and disease, especially in most cancers.
Telomere length was shortened in workers exposed to polycyclic aromatic hydrocarbons …

miRNAs: A potentially valuable tool in pesticide toxicology assessment-current experimental and epidemiological data review

R Valencia-Quintana, IU Bahena-Ocampo… - Chemosphere, 2022 - Elsevier
Abstract miRNAs are responsible for the regulation of many cellular processes such as
development, cell differentiation, proliferation, apoptosis, and tumor growth. Several studies …

Polycyclic aromatic hydrocarbon exposure, miRNA genetic variations, and associated leukocyte mitochondrial DNA copy number: a cross-sectional study in China

X Duan, Y Yang, H Zhang, B Liu, W Wei, L Wang… - Chemosphere, 2020 - Elsevier
Mitochondria DNA was preferentially attacked by the exogenous carcinogens including
polycyclic aromatic hydrocarbons (PAHs) relative to nuclear DNA, and nuclear gene variants …

MicroRNAs as potential biomarkers of insecticide exposure: a review

J Qiao, Y Du, J Yu, J Guo - Chemical Research in Toxicology, 2019 - ACS Publications
Insecticides are key weapons for the control of pests. Large scale use of insecticides is
harmful to the ecosystem, which is made up of a wide range of species and environments …