Immunology of human fibrosis
M Bhattacharya, P Ramachandran - Nature Immunology, 2023 - nature.com
Fibrosis, defined by the excess deposition of structural and matricellular proteins in the
extracellular space, underlies tissue dysfunction in multiple chronic diseases. Approved …
extracellular space, underlies tissue dysfunction in multiple chronic diseases. Approved …
[HTML][HTML] Dynamic links between mechanical forces and metabolism shape the tumor milieu
Cell function relies on the spatiotemporal dynamics of metabolic reactions. In all
physiopathological processes of tissues, mechanical forces impact the structure and function …
physiopathological processes of tissues, mechanical forces impact the structure and function …
[HTML][HTML] The microenvironment dictates glycocalyx construction and immune surveillance
Efforts to identify anti-cancer therapeutics and understand tumor-immune interactions are
built with in vitro models that do not match the microenvironmental characteristics of human …
built with in vitro models that do not match the microenvironmental characteristics of human …
Arginase 1 is a Key Driver of Immune Suppression and a Therapeutic Target of Pancreatic Cancer
R Menjivar - 2022 - deepblue.lib.umich.edu
Pancreatic ductal adenocarcinoma (PDA) is the most common form of pancreatic cancer.
PDA is a lethal disease with a 5-year survival rate of less than 11% after diagnosis. Some of …
PDA is a lethal disease with a 5-year survival rate of less than 11% after diagnosis. Some of …