Osteoarthritis (OA) and rheumatoid arthritis (RA) are both debilitating diseases that cause
significant morbidity in the US population. Extracellular vesicles (EVs), including exosomes …

Systemic lupus erythematosus (SLE) is an autoimmune chronic inflammatory disease of
unknown etiology, although genetic and environmental factors appear to contribute to its …

The autoimmune disorder rheumatoid arthritis (RA) causes chronic inflammation and
destruction of joints. T cells are a predominant component of the synovial environment in …

Purpose The communication of cell injury and death is a critical element in host defense.
Although immune cells can serve this function by elaborating cytokines and chemokines …

Thrombosis and cardiovascular complications are common manifestations of a variety of
pathological conditions, including infections and chronic inflammatory diseases. Hence …

Juvenile dermatomyositis (JDM) is a rare autoimmune disease mainly characterized by
muscle and skin involvement. Vasculopathy is considered central to the pathogenesis of the …

Patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) demonstrate
increased circulating microparticles (MP). These vesicles, primarily those that form immune …

Background Endothelial activation and damage is commonly observed in patients with
systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) and is related to …

Communication between natural killer cells (NK cells) and monocytes/macrophages may
play an important role in immunomodulation and regulation of inflammatory processes. The …

Patients with rheumatoid arthritis (RA) and autoantibodies, such as rheumatoid factor and
those against cyclic citrullinated peptides, are designated as seropositive and have a more …