A review on synthesis, reactions and biological properties of seven membered heterocyclic compounds: azepine, azepane, azepinone
M Kaur, S Garg, DS Malhi… - Current Organic Chemistry, 2021 - ingentaconnect.com
Seven membered heterocyclic Azepine and its derivatives have great pharmacological and
therapeutic implications. In this review, the literature of the last fifty years has been exploited …
therapeutic implications. In this review, the literature of the last fifty years has been exploited …
Pimenta dioica (L.) Merr. Bioactive Constituents Exert Anti-SARS-CoV-2 and Anti-Inflammatory Activities: Molecular Docking and Dynamics, In Vitro, and In Vivo …
In response to the urgent need to control Coronavirus disease 19 (COVID-19), this study
aims to explore potential anti-SARS-CoV-2 agents from natural sources. Moreover, cytokine …
aims to explore potential anti-SARS-CoV-2 agents from natural sources. Moreover, cytokine …
Computational and experimental characterisation of a new (R)-camphor-Thiazolidinone derivative: A combined approach for structure optimisation and activity …
This study describes the synthesis, characterisation, in-silico exploration, and theoretical
investigation of a novel 5-Methyl-2-(((1S, 4R)-1, 7, 7-trimethylbicyclo [2.2. 1] heptan-2 …
investigation of a novel 5-Methyl-2-(((1S, 4R)-1, 7, 7-trimethylbicyclo [2.2. 1] heptan-2 …
Benzotriazepine synthesis, conformational analysis, and biological properties
SM Harvey, X Wei, D Truong… - Canadian Journal of …, 2024 - cdnsciencepub.com
Various benzotriazepine ring systems have been synthesized and examined for biological
activity. Moreover, the 1, 3, 4-benzotriazepin-2-one has been shown to act as a constrained …
activity. Moreover, the 1, 3, 4-benzotriazepin-2-one has been shown to act as a constrained …
Synthesis, molecular docking, and biological evaluation of a new series of benzothiazinones and their benzothiazinyl acetate derivatives as anticancer agents against …
F Ramzan, SA Nabi, MS Lone, K Imtiyaz, L Urooj… - ACS …, 2023 - ACS Publications
Six 1, 4-benzothiazin-3-ones (2a–f) and four benzothiazinyl acetate derivatives (3a–d) were
synthesized and characterized by various spectroscopic methods, namely, 1H NMR, 13C …
synthesized and characterized by various spectroscopic methods, namely, 1H NMR, 13C …
Synthesis and cytotoxic activity of certain benzothiazole derivatives against human MCF‐7 cancer cell line
LW Mohamed, AT Taher, GS Rady… - Chemical Biology & …, 2017 - Wiley Online Library
A new series of benzothiazole has been synthesized as cytotoxic agents. The new
derivatives were tested for their cytotoxic activity toward the human breast cancer MCF‐7 …
derivatives were tested for their cytotoxic activity toward the human breast cancer MCF‐7 …
Isatoic anhydride: a fascinating and basic molecule for the synthesis of substituted quinazolinones and benzo di/triazepines
Z Tashrifi… - Current Organic …, 2019 - ingentaconnect.com
This review article is focused on the synthesis of compounds with quinazolinones and benzo
di/triazepine scaffolds. These invaluable derivatives are of great interest in medicinal and …
di/triazepine scaffolds. These invaluable derivatives are of great interest in medicinal and …
Synthesis of 4-Aryl-1, 3, 4-benzotriazepinones from Isatoic Anhydrides and Hydrazonyl Chlorides
X Zhang, Y Pan, T Liu, Y Wang - The Journal of Organic …, 2023 - ACS Publications
An efficient synthesis of 4-aryl-1, 3, 4-benzotriazepinones from readily available isatoic
anhydrides and hydrazonyl chlorides was developed. In this facile protocol, a series of …
anhydrides and hydrazonyl chlorides was developed. In this facile protocol, a series of …
Ultrasound-promoted one-pot four-component synthesis of novel biologically active 3-aryl-2, 4-dithioxo-1, 3, 5-triazepane-6, 7-dione and their toxicity investigation
NO Mahmoodi, M Mohammadi Zeydi… - Journal of Sulfur …, 2016 - Taylor & Francis
We have described a novel four-component reaction (4MCR) between oxalyl chloride 1,
anilines 2a–h, and two molecules of ammonium thiocyanate 3 in acetone under ultrasound …
anilines 2a–h, and two molecules of ammonium thiocyanate 3 in acetone under ultrasound …