Fermented foods, health and the gut microbiome

NK Leeuwendaal, C Stanton, PW O'toole, TP Beresford - Nutrients, 2022 - mdpi.com
Fermented foods have been a part of human diet for almost 10,000 years, and their level of
diversity in the 21st century is substantial. The health benefits of fermented foods have been …

Host–microbiota maladaptation in colorectal cancer

A Janney, F Powrie, EH Mann - Nature, 2020 - nature.com
Colorectal cancer (CRC) is a heterogeneous disease of the intestinal epithelium that is
characterized by the accumulation of mutations and a dysregulated immune response. Up to …

[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …

[HTML][HTML] Gut microbiota modulation: a novel strategy for prevention and treatment of colorectal cancer

W Fong, Q Li, J Yu - Oncogene, 2020 - nature.com
Research about the role of gut microbiome in colorectal cancer (CRC) is a newly emerging
field of study. Gut microbiota modulation, with the aim to reverse established microbial …

Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis

N Sugimura, Q Li, ESH Chu, HCH Lau, W Fong, W Liu… - Gut, 2022 - gut.bmj.com
Objective Using faecal shotgun metagenomic sequencing, we identified the depletion of
Lactobacillus gallinarum in patients with colorectal cancer (CRC). We aimed to determine …

Gut microbiome, big data and machine learning to promote precision medicine for cancer

G Cammarota, G Ianiro, A Ahern, C Carbone… - Nature reviews …, 2020 - nature.com
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …

Akkermansia muciniphila is a promising probiotic

T Zhang, Q Li, L Cheng, H Buch… - Microbial …, 2019 - Wiley Online Library
Summary Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the
mucosal layer, is considered to be a promising candidate as probiotics. A. muciniphila is …

Diverging inflammasome signals in tumorigenesis and potential targeting

R Karki, TD Kanneganti - Nature Reviews Cancer, 2019 - nature.com
Inflammasomes are molecular platforms that assemble upon sensing various intracellular
stimuli. Inflammasome assembly leads to activation of caspase 1, thereby promoting the …

The oral microbiome and cancer

M Irfan, RZR Delgado, J Frias-Lopez - Frontiers in immunology, 2020 - frontiersin.org
There is mounting evidence that members of the human microbiome are highly associated
with a wide variety of cancer types. Among oral cancers, oral squamous cell carcinoma …

Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity

X Long, CC Wong, L Tong, ESH Chu, C Ho Szeto… - Nature …, 2019 - nature.com
Emerging evidence implicates a role of the gut microbiota in colorectal cancer (CRC).
Peptostreptococcus anaerobius (P. anaerobius) is an anaerobic bacterium selectively …