Acromegaly is caused by excess growth hormone (GH) secretion emanating from a
somatotroph adenoma. High GH and Insulin-like growth factor-1 (IGF-1) levels lead to acral …

Purpose Systematic review and meta-analysis comparing endoscopic and microscopic
transsphenoidal surgery for Cushing's disease regarding surgical outcomes (remission …

Context: GH-secreting pituitary adenomas exhibit heterogeneous natural history ranging
from small tumors to large aggressive adenomas. Objective: To rigorously classify an …

Giant pituitary adenomas comprise about 6–10% of all pituitary tumors. They are mostly
clinically non-functioning adenomas and occur predominantly in males. The presenting …

Purpose Surgical experience is considered paramount for excellent outcome of
transsphenoidal surgery (TSS). However, objective data demonstrating the surgical success …

OBJECT Craniopharyngiomas and similar midline suprasellar tumors have traditionally
been resected via transcranial approaches. More recently, expanded endoscopic endonasal …

BACKGROUND: Long-term remission rates from endoscopic transsphenoidal surgery for
acromegaly and their relationship to prognostic indicators of disease aggressiveness are not …

Purpose We report the efficacy and safety of transsphenoidal microsurgery in a large and
homogeneous cohort of patients with pituitary adenomas (PAs) treated at a single Institute …

Objective To evaluate the safety and efficacy of the endoscopic endonasal transsphenoidal
approach (EETA) for nonfunctioning pituitary adenoma (NFPA) in the elderly population …

Object Transient delayed postoperative hyponatremia (DPH) after transsphenoidal surgery
(TSS) is common and can have potentially devastating consequences. However, the true …