[HTML][HTML] Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases
The antiviral DNA cytosine deaminase APOBEC3B has been implicated as a source of
mutation in many cancers. However, despite years of work, a causal relationship has yet to …
mutation in many cancers. However, despite years of work, a causal relationship has yet to …
DNA deamination is required for human APOBEC3A-driven hepatocellular carcinoma in vivo
JA Naumann, PP Argyris, MA Carpenter… - International journal of …, 2023 - mdpi.com
Although the APOBEC3 family of single-stranded DNA cytosine deaminases is well-known
for its antiviral factors, these enzymes are rapidly gaining attention as prominent sources of …
for its antiviral factors, these enzymes are rapidly gaining attention as prominent sources of …
[HTML][HTML] Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
The antiviral DNA cytosine deaminase APOBEC3B has been implicated as a source of
mutation in many different cancers. Despite over 10 years of work, a causal relationship has …
mutation in many different cancers. Despite over 10 years of work, a causal relationship has …
[PDF][PDF] Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo
S Mendez Ruiz, AM Chalk, A Goradia… - NAR …, 2023 - academic.oup.com
Adenosine to inosine editing (A-to-I) in regions of double stranded RNA (dsRNA) is
mediated by adenosine deaminase acting on RNA 1 (ADAR1) or ADAR2. ADAR1 and A-to-I …
mediated by adenosine deaminase acting on RNA 1 (ADAR1) or ADAR2. ADAR1 and A-to-I …