Advances in high throughput cell culture technologies for therapeutic screening and biological discovery applications

H Ryoo, H Kimmel, E Rondo… - … & Translational Medicine, 2024 - Wiley Online Library
Cellular phenotypes and functional responses are modulated by the signals present in their
microenvironment, including extracellular matrix (ECM) proteins, tissue mechanical …

Granular Biomaterials as Bioactive Sponges for the Sequestration and Release of Signaling Molecules

DB Emiroglu, A Singh, B Marco‐Dufort… - Advanced …, 2024 - Wiley Online Library
A major challenge for the regeneration of chronic wounds is an underlying dysregulation of
signaling molecules, including inflammatory cytokines and growth factors. To address this …

Combinatorial microgels for 3D ECM screening and heterogeneous microenvironmental culture of primary human hepatic stellate cells

H Ryoo, R Giovanni, H Kimmel, I Jain… - Advanced …, 2024 - Wiley Online Library
Nonalcoholic fatty liver disease affects 30% of the United States population and its
progression can lead to nonalcoholic steatohepatitis (NASH), and increased risks for …