Gallbladder cancer-associated genetic variants rs1003349 and rs1004030 regulate MMP14 expression by altering SOX10-and MYB-binding sites

A Palo, K Besra, M Dixit - Human Molecular Genetics, 2023 - academic.oup.com
The pathogenesis of gallbladder cancer is complex, involving environmental and genetic
risk factors. The matrix metallopeptidase 14 (MMP14) alters the tumor microenvironment and …

An integrated approach to identify critical transcription factors in the protection against hydrogen peroxide-induced oxidative stress by Danhong injection

J Zhang, F Guo, J Wei, M Xian, S Tang, Y Zhao… - Free Radical Biology …, 2017 - Elsevier
Oxidative stress plays a vital role in many pathological processes of the cardiovascular
diseases. However, the underlying mechanism remains unclear, especially on a …

[HTML][HTML] APEX1 promotes the oncogenicity of hepatocellular carcinoma via regulation of MAP2K6

Z Sun, G Chen, L Wang, Q Sang, G Xu… - Aging (Albany NY …, 2022 - ncbi.nlm.nih.gov
Objective: Apurinic/apyrimidinic endonuclease 1 (APEX1), a key enzyme responsible for
DNA base excision repair, has been linked to development and progression of cancers. In …

Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu

J Zhang, Y Geng, F Guo, F Zhang, M Liu, L Song… - Scientific Reports, 2017 - nature.com
Oxidative stress initiates harmful cellular responses, such as DNA damage and protein
denaturation, triggering a series of cardiovascular disorders. Systematic investigations of the …

多功能蛋白APE1/Ref1 在肝衰竭大鼠肝细胞不同部位的表达意义

刁建新, 代欢, 李海叶, 杨运高 - 实用肝脏病杂志, 2016 - manu43.magtech.com.cn
目的研究多功能蛋白酶脱嘌呤/脱嘧啶核酸内切酶(APE1/Ref1) 在慢加急性肝衰竭大鼠肝细胞
不同部位的表达意义. 方法将30 只SD 大鼠随机分为对照组(n= 15) 和模型组(n= 15) …

GZMK facilitates RA progression by activating the ERK signaling by interacting with CCL5

C Sun, L Wang, Q Yan, J Wang, C Liu, N Lin - 2024 - researchsquare.com
Objective Synovial over-proliferation is a key event in the progression of rheumatoid arthritis
(RA) disease. Ferroptosis may be essential for maintaining the balance between synovial …

Chemotherapeutic Drugs and Gallbladder Cancer: Market Potential in India

R Dixit, M Pandey, P Pandey, VK Shukla - Bioeconomy for Sustainable …, 2020 - Springer
Gallbladder cancer (GBC) is the most fatal cancer of the biliary tract with poor prognosis.
Silent in its infancy, this malignancy remains asymptomatic until aggressive disease has …

[PDF][PDF] Defeng Li1, Yi Zhang1, Haiyu Xu1 & Hongjun Yang1

J Zhang, Y Geng, F Guo, F Zhang, M Liu, L Song, Y Ma - d-nb.info
Materials and Methods Preparation of YXS Intestinal Absorption Liquid. Experimental
Animal Center of Peking University Health Science Center, Beijing, China (certificate no …