The aging process results in multiple traceable footprints, which can be quantified and used
to estimate an organism's age. Examples of such aging biomarkers include epigenetic …

Telomeres, the DNA–protein structures located at the ends of chromosomes, have been
proposed to act as a biomarker of aging. In this review, the human evidence that telomere …

The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …

As the global population faces a progressive shift towards a higher median age,
understanding the mechanisms underlying healthy brain ageing has become of paramount …

Senescence is a state of permanent cell cycle arrest. Cellular senescence can promote
tissue remodelling but can negatively affect regenerative capacities of tissues and contribute …

Telomerase is perceived as an immortality enzyme that might provide longevity to cells and
whole organisms. Importantly, it is generally inactive in most somatic cells of healthy, adult …

Evidence assembled over the last decade shows that average telomere length (TL) acts as a
biomarker for biological aging and cardiovascular disease (CVD) in particular. Although …

Schizophrenia is associated with a number of anatomical and physiological abnormalities
outside of the brain, as well as with a decrease in average life span estimated at 20% in the …

Aging affects most living organisms and includes the processes that reduce health and
survival. The chronological and the biological age of individuals can differ remarkably, and …

Objective We investigated the relationship between diabetes and telomere length by meta-
analysis. Methods We searched five popular databases for articles published between 1990 …