Can we consider cancer to be a “metabolic disease”? Tumors are the result of a metabolic
selection, forming tissues composed of heterogeneous cells that generally express an …

Abstract Background Silicon (Si) has been known to regulate plant growth; however, the
underlying mechanisms of short-term exogenous Si application on the regulation of calcium …

Abstract Ribose-5-phosphate isomerase A (RpiA; EC 5.3. 1.6) interconverts ribose-5-
phosphate and ribulose-5-phosphate. This enzyme plays essential roles in carbohydrate …

During diabetes mellitus, advanced glycation end-products (AGEs) are major contributors to
the development of alterations in cerebral capillaries, leading to the disruption of the blood …

Aspergillus fumigatus is a devastating opportunistic fungal pathogen causing hundreds of
thousands of deaths every year. Phosphoglucose isomerase (PGI) is a glycolytic enzyme …

l-Arabinose isomerase (AI) catalyzes the isomerization of l-arabinose to l-ribulose. It can
also convert d-galactose to d-tagatose at elevated temperatures in the presence of divalent …

Colias eurytheme butterflies display extensive allozyme polymorphism in the enzyme
phosphoglucose isomerase (PGI). Earlier studies on biochemical and fitness effects of these …

Phosphoglucose isomerase (PGI) catalyzes the interconversion of fructose-6-phosphate and
glucose-6-phosphate, which impacts cell carbon metabolic flow. Arabidopsis (Arabidopsis …

Sugar and organic acids are important factors determining pitaya fruit quality. However,
changes in sugars and acids, and expressions of metabolism-associated genes during fruit …

Understanding the catalytic efficiency and specificity of enzymes is a fundamental question
of major practical and conceptual importance in biochemistry. Although progress in …