Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential
for proper “education” of the immune system. Intestinal microbial communities are able to …

Mast cells were discovered more than 100 years ago and until recently, have been
considered renegades of the host with the sole purpose of perpetuating allergy. The …

T regulatory (Treg) cells play a role in the suppression of immune responses, thus serving to
induce tolerance and control autoimmunity. Here, we explored whether Treg cells influence …

Introduction Mast cells are found in all tissues and express numerous surface receptors
allowing them to sense and respond to allergic, autoimmune, environmental …

Mast cells play a critical role in inflammatory diseases and tumor growth. The versatility of
mast cells is reflected in their ability to secrete a wide range of biologically active cytokines …

Alopecia areata (AA) is a CD8+ T-cell dependent autoimmune disease of the hair follicle
(HF) in which the collapse of HF immune privilege (IP) plays a key role. Mast cells (MCs) are …

There are many parallels between allergic and autoimmune responses. Both are considered
hypersensitivity responses: pathologies that are elicited by an exuberant reaction to …

Background We recently reported that various environmental estrogens induce mast cell
degranulation and enhance IgE-mediated release of allergic mediators in vitro. Objectives …

Mast cells are multifunctional master cells implicated in both innate and adaptive immune
responses. Their role has been best characterized in allergy and anaphylaxis; however …

Effector T cell development is directly driven by APCs, in particular, by antigen‐primed
dendritic cells (DCs). Depending on the pathogenic stimulus and the microenvironment …