Role of the insulin-like growth factor family in cancer development and progression

H Yu, T Rohan - Journal of the National Cancer Institute, 2000 - academic.oup.com
The insulin-like growth factors (IGFs) are mitogens that play a pivotal role in regulating cell
proliferation, differentiation, and apoptosis. The effects of IGFs are mediated through the IGF …

Alcohol use and breast cancer: a critical review

KD Shield, I Soerjomataram… - Alcoholism: Clinical and …, 2016 - Wiley Online Library
The objective of this study was to outline the biological pathways of alcohol‐attributable
breast cancer, the epidemiological risk relationship between alcohol consumption and …

Bone mineral density, serum insulin-like growth factor I, and bone turnover markers in viral cirrhosis

FJ Gallego-Rojo, JL Gonzalez-Calvin… - Hepatology, 1998 - journals.lww.com
Previous studies suggest that low bone mass is a complication of alcoholic liver disease.
Nevertheless, little is known about bone mass and bone metabolism in viral cirrhosis. To …

Sarcopenia in alcoholic liver disease: clinical and molecular advances

J Dasarathy, AJ McCullough… - Alcoholism: Clinical and …, 2017 - Wiley Online Library
Despite advances in treatment of alcohol use disorders that focus on increasing abstinence
and reducing recidivism, alcoholic liver disease (ALD) is projected to be the major cause of …

[HTML][HTML] Emerging role of liver-bone axis in osteoporosis

H Gao, X Peng, N Li, L Gou, T Xu, Y Wang, J Qin… - Journal of Orthopaedic …, 2024 - Elsevier
Background Increasing attention to liver-bone crosstalk has spurred interest in targeted
interventions for various forms of osteoporosis. Liver injury induced by different liver …

Contributions of net hepatic glycogenolysis and gluconeogenesis to glucose production in cirrhosis

KF Petersen, M Krssak, V Navarro… - American Journal …, 1999 - journals.physiology.org
Net hepatic glycogenolysis and gluconeogenesis were examined in normal (n= 4) and
cirrhotic (n= 8) subjects using two independent methods [13C nuclear magnetic resonance …

Alcohol intake and risk of lethal prostate cancer in the health professionals follow-up study

MK Downer, SA Kenfield, MJ Stampfer… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE It is unknown whether alcohol intake is associated with the risk of lethal
(metastatic or fatal) prostate cancer. We examine (1) whether alcohol intake among men at …

Age, sex, and smoking are predictors of circulating insulin-like growth factor 1 and insulin-like growth factor–binding protein 3

VG Kaklamani, A Linos, E Kaklamani… - Journal of Clinical …, 1999 - ascopubs.org
PURPOSE: Insulin-like growth factor (IGF-1) and its major binding protein (IGF-BP3) have
recently been implicated in the pathogenesis of several malignancies. However …

Alcohol intake, drinking patterns, and risk of prostate cancer in a large prospective cohort study

EA Platz, MF Leitzmann, EB Rimm… - American journal of …, 2004 - academic.oup.com
Alcohol drinking has been extensively studied in relation to prostate cancer, yet findings on
the direction of the association are equivocal. Previous studies have not examined drinking …

Osteopenia assessed by body composition analysis is related to malnutrition in alcoholic patients

F Santolaria, E González-Reimers, JL Pérez-Manzano… - Alcohol, 2000 - Elsevier
Osteopenia is frequent among alcoholics. Its pathogenesis seems to be multifactorial,
including ethanol intake, hormonal changes, liver cirrhosis, and malnutrition. Our objective is …