Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

Excessive reactive oxygen species Revised abstract, especially superoxide anion (O2•−),
play important roles in the pathogenesis of many cardiovascular diseases, including …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Peroxynitrite—the product of the diffusion-controlled reaction of nitric oxide with superoxide
radical—is a short-lived oxidant species that is a potent inducer of cell death. Conditions in …

Copper (Cu), a redox active metal, is an essential nutrient for all species studied to date.
During the past decade, there has been increasing interest in the concept that marginal …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

▪ Abstract Copper-zinc superoxide dismutase (CuZnSOD, SOD1 protein) is an abundant
copper-and zinc-containing protein that is present in the cytosol, nucleus, peroxisomes, and …

There is growing evidence that oxidative stress contributes to hypertension. Oxidative stress
can precede the development of hypertension. In almost all models of hypertension, there is …

Protein 3-nitrotyrosine is a posttranslational modification found in many pathological
conditions from acute to chronic diseases. Could 3-nitrotyrosine formation participate on the …

Parkinson's disease (PD) pathology is characterized by the abnormal accumulation and
aggregation of the pre-synaptic protein α-synuclein in the dopaminergic neurons as Lewy …