[HTML][HTML] Uric acid in inflammation and the pathogenesis of atherosclerosis
Y Kimura, D Tsukui, H Kono - International journal of molecular sciences, 2021 - mdpi.com
Hyperuricemia is a common metabolic syndrome. Elevated uric acid levels are risk factors
for gout, hypertension, and chronic kidney diseases. Furthermore, various epidemiological …
for gout, hypertension, and chronic kidney diseases. Furthermore, various epidemiological …
[HTML][HTML] The relationships among hyperuricemia, endothelial dysfunction, and cardiovascular diseases: molecular mechanisms and clinical implications
P Puddu, GM Puddu, E Cravero, L Vizioli, A Muscari - Journal of cardiology, 2012 - Elsevier
Uric acid is the end product of purine metabolism. Its immediate precursor, xanthine, is
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …
converted to uric acid by an enzymatic reaction involving xanthine oxidoreductase. Uric acid …
Review of hyperuricemia as new marker for metabolic syndrome
L Billiet, S Doaty, JD Katz… - International Scholarly …, 2014 - Wiley Online Library
Hyperuricemia has long been established as the major etiologic factor in gout. In recent
years, a large body of evidence has accumulated that suggests that hyperuricemia may play …
years, a large body of evidence has accumulated that suggests that hyperuricemia may play …
Lesinurad in combination with allopurinol: a randomised, double-blind, placebo-controlled study in patients with gout with inadequate response to standard of care …
T Bardin, RT Keenan, PP Khanna, J Kopicko… - Annals of the …, 2017 - ard.bmj.com
Objectives Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added
to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised …
to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised …
Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout
F Perez-Ruiz, L Martínez-Indart, L Carmona… - Annals of the …, 2014 - ard.bmj.com
Background While several studies have reported a link between the presence of gout and
adverse cardiovascular (CV) events in the general population, none has addressed the …
adverse cardiovascular (CV) events in the general population, none has addressed the …
Uric acid as one of the important factors in multifactorial disorders–facts and controversies
D Pasalic, N Marinkovic, L Feher-Turkovic - Biochemia medica, 2012 - hrcak.srce.hr
Sažetak With considering serum concentration of the uric acid in humans we are observing
hyperuricemia and possible gout development. Many epidemiological studies have shown …
hyperuricemia and possible gout development. Many epidemiological studies have shown …
Harnessing hyperuricemia to atherosclerosis and understanding its mechanistic dependence
M Jayachandran, S Qu - Medicinal research reviews, 2021 - Wiley Online Library
Atherosclerosis is regarded as the disease of the arterial vasculature. The main
characteristics of atherosclerosis are the abnormal accumulation of lipids, increased …
characteristics of atherosclerosis are the abnormal accumulation of lipids, increased …
Uric acid and cardiometabolic diseases
SJ Lee, BK Oh, KC Sung - Clinical hypertension, 2020 - Springer
Hyperuricemia, which has been considered as a cause of gout and nephrolithiasis has
recently been suggested to be associated with hypertension, coronary heart disease, heart …
recently been suggested to be associated with hypertension, coronary heart disease, heart …
Silent monosodium urate crystal deposits are associated with severe coronary calcification in asymptomatic hyperuricemia: an exploratory study
M Andrés, MA Quintanilla, F Sivera… - Arthritis & …, 2016 - Wiley Online Library
Objective To evaluate the association between monosodium urate (MSU) crystal deposits in
patients with asymptomatic hyperuricemia and the severity and extension of coronary artery …
patients with asymptomatic hyperuricemia and the severity and extension of coronary artery …
[HTML][HTML] Hyperuricemia and cardiovascular risk
L Shahin, KM Patel, MK Heydari, MM Kesselman - Cureus, 2021 - ncbi.nlm.nih.gov
As the prevalence of hyperuricemia (elevated uric acid levels in the blood) increases, the
relationship between serum uric acid levels and cardiovascular risk has garnered increased …
relationship between serum uric acid levels and cardiovascular risk has garnered increased …