DNA-Based Nonviral Gene Therapy─ Challenging but Promising

X Guan, Y Pei, J Song - Molecular Pharmaceutics, 2024 - ACS Publications
Over the past decades, significant progress has been made in utilizing nucleic acids,
including DNA and RNA molecules, for therapeutic purposes. For DNA molecules, although …

One-Step Synthesis of Peptide–Gold Nanoclusters with Tunable Fluorescence and Enhanced Gene Delivery Efficiency

Z Wang, C Tang, M Huang, X Rong, H Lin, R Su… - Langmuir, 2022 - ACS Publications
In this study, peptide–gold nanoclusters with tunable fluorescence were prepared by a
simple “one-pot” method, which were used for gene localization and delivery in vivo to …

Surface chemistry of spiky silica nanoparticles tailors polyethyleneimine binding and intracellular DNA delivery

D Cheng, S Theivendran, J Tang, L Cai, J Zhang… - Journal of Colloid and …, 2022 - Elsevier
Cellular delivery of DNA using silica nanoparticles has attracted great attention. Typically,
polyethyleneimine (PEI) is used to form a silica/PEI composite vector. Understanding the …

Engineered Silica Nanoparticles for Nucleic Acid Delivery

Y Zhang, Y Yu, Y Yang, Y Wang, C Yu - Small Methods, 2024 - Wiley Online Library
The development of nucleic acid‐based drugs holds great promise for therapeutic
applications, but their effective delivery into cells is hindered by poor cellular membrane …

[HTML][HTML] Mesoporous organosilica nanoparticles with tetrasulphide bond to enhance plasmid DNA delivery

Y Zhang, H Xian, E Strounina, KS Gunther, MJ Sweet… - Pharmaceutics, 2023 - mdpi.com
Pharmaceutics | Free Full-Text | Mesoporous Organosilica Nanoparticles with Tetrasulphide
Bond to Enhance Plasmid DNA Delivery Next Article in Journal In Silico Pharmacology for …

Evaluation of silica nanoparticles cytotoxicity (20-40 nm) on cancerous epithelial cell (A549) and fibroblasts cells of human normal lung fibroblast (MRC5)

T Karimi, N Najmoddin… - Occupational …, 2021 - publish.kne-publishing.com
Introduction: Silica nanoparticles have received more attraction in medical and industrial
applications due to their unique properties such as small size, the possibility of surface …

[HTML][HTML] ارزیابی اثر سایتوتوکسیک نانوذرات سیلیکا با اندازه nm40-20 بر سلول‌های سرطانی اپیتلیال ریوی (A549) و فیبروبلاست نرمال ریوی انسان (MRC5)

کریمی, طناز, نجم الدین, منهاج بنا, رابعه - فصلنامه طب کار, 2021‎ - tkj.ssu.ac.ir
ارزیابی اثر سایتوتوکسیک نانوذرات سیلیکا با اندازه nm40-20 بر سلول‌های سرطانی اپیتلیال
ریوی(A549) و فیبروبلاست نرمال ریوی انسان (MRC5) - فصلنامه طب کار فصلنامه طب کار …