Sarcopenia is the age‐related decline in muscle mass and function without any underlying
disease. The exact molecular mechanisms responsible for this pathology remain unknown …

Exercise is a nonpharmacological intervention that improves health during aging and a
valuable tool in the diagnostics of aging-related diseases. In muscle, exercise transiently …

Aging is accompanied by a progressive decline in mitochondrial function, which in turn
contributes to a variety of age-related diseases. Counterintuitively, a growing number of …

Regular physical exercise is the most efficient and accessible intervention known to promote
healthy aging in humans. The molecular and cellular mechanisms that mediate system-wide …

Sarcopenia, the age-related decline of muscle, is a significant and growing public health
burden. C. elegans, a model organism for investigating the mechanisms of ageing, also …

Sarcopenia is a syndrome of age-related loss of muscle mass and strength that seriously
affects human health, and there are currently no effective drugs to treat the disease …

In this study, we report a microfluidic device for the whole-life culture of the nematode
Caenorhabditis elegans that allows the scoring of animal survival and health measures. This …

Mitochondria play a crucial role in cellular respiration, ATP production, and the regulation of
various cellular processes. Mitochondrial dysfunctions have been directly linked to …

The nematode C. elegans is a leading model to investigate the mechanisms of stress-
induced behavioral changes coupled with biochemical mechanisms. Our group has …

Dietary restriction (DR) and dietary deprivation (DD) have been shown to be significantly
beneficial in terms of lifespan gains and stress alleviation in invertebrate and vertebrate …