The CD8+ T Cell Noncytotoxic Antiviral Responses

MG Morvan, FC Teque, CP Locher… - … and Molecular Biology …, 2021 - Am Soc Microbiol
The CD8+ T cell noncytotoxic antiviral response (CNAR) was discovered during studies of
asymptomatic HIV-infected subjects more than 30 years ago. In contrast to CD8+ T cell …

[HTML][HTML] Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161++TCR iVα7.2+ Mucosal …

YK Yong, A Saeidi, HY Tan, M Rosmawati… - Frontiers in …, 2018 - frontiersin.org
Mucosal-associated invariant T (MAIT) cells, defined as CD161++ TCR iVα7. 2+ T cells, play
an important role in the innate defense against bacterial infections, and their functionality is …

[HTML][HTML] Chronic infections: a possible scenario for autophagy and senescence cross-talk

MO Aguilera, LR Delgui, PS Romano, MI Colombo - Cells, 2018 - mdpi.com
Multiple tissues and systems in the organism undergo modifications during aging due to an
accumulation of damaged proteins, lipids, and genetic material. To counteract this process …

Functional modulation of CD8+ T cell by approved novel immune enhancer: Nocardia rubra Cell-Wall Skeletons (Nr-CWS)

Y Tao, G Wang, J Zhai, N Zhang - International Immunopharmacology, 2020 - Elsevier
Nocardia rubra cell wall skeleton (Nr-CWS) has been reported to have innate
immunostimulating and anti-tumor activities. However, the immunomodulatory effects of Nr …

PKM2 is required to activate myeloid dendritic cells from patients with severe aplastic anemia

C Liu, M Zheng, T Wang, H Jiang, R Fu… - Oxidative medicine …, 2018 - Wiley Online Library
Severe aplastic anemia (SAA) is an autoimmune disease in which bone marrow failure is
mediated by activated myeloid dendritic cells (mDCs) and T lymphocytes. Recent research …

[HTML][HTML] Characterization of peripheral cytokine-secreting cells responses in HIV/TB co-infection

Y Tan, W Guo, Q Zhu, S Song, Y Xiang, S Wu… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Currently the responses of peripheral cytokine-secreting cells in the natural
course of human immunodeficiency virus (HIV) and tuberculosis (TB) co-infection haven't …

[HTML][HTML] Elevated expression of miR-155 is associated with the differentiation of CD8+ T cells in patients with HIV-1

C Jin, L Cheng, X Lu, T Xie… - Molecular medicine …, 2017 - spandidos-publications.com
The differentiation and response ofCD8+ T cells is vital in host defense against human
immunodeficiency virus type 1 (HIV-1). MicroRNA (miR)‑155 is an important regulator of T …

[HTML][HTML] Decreased expression of perforin in CD8+ T lymphocytes in patients with Mycobacterium tuberculosis infection and its potential value as a marker for efficacy …

H Jiang, H Gong, Q Zhang, J Gu, L Liang… - Journal of Thoracic …, 2017 - ncbi.nlm.nih.gov
Background Cytolytic activity against mycobacteria tuberculosis (MTB) within the infected
macrophage is a crucial step in the immunity against TB infection, as MTB is an intracellular …

[HTML][HTML] Dendritic cells modified by tumor associated antigen SMP30 have enhanced antitumor effect against mouse hepatocarcinoma cells in vitro and in vivo

J Guo, Y Zhang, Q Qin, N Chao, T Huang… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Tumor immunotherapy based on dendritic cells (DC) is one of the most
promising approaches to treat cancers. This therapy uses an immunogenic tumor antigen to …

Respuesta inmunitaria de una población del Caribe colombiano infectada con el virus chikungunya

JJ Raad, AS Rosero, JV Martínez, A Parody… - Revista Colombiana de …, 2016 - Elsevier
Introducción La infección por el virus chikungunya se ha convertido en un problema de
salud pública, tanto por su afección inmediata sobre la salud y calidad de vida de los …