Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine

LA Baltina - Current medicinal chemistry, 2003 - ingentaconnect.com
Glycyrrhizic Acid (GL) is the major bioactive triterpene glycoside of licorice root (Glycyrrhiza
Radix) extracts possessing a wide range of pharmacological properties (anti-inflammatory …

A focused review of synthetic applications of Lawesson's reagent in organic synthesis

H Khatoon, E Abdulmalek - Molecules, 2021 - mdpi.com
Lawesson's reagent (LR) is a well-known classic example of a compound with unique
construction and unusual chemical behavior, with a wide range of applications in synthetic …

[PDF][PDF] Betulin and its derivatives. Chemistry and biological activity

GA Tolstikov, OB Flekhter, EE Shultz… - Chemistry for …, 2005 - researchgate.net
The data on natural sources of betulin and methods of its extraction are systematized in the
review. Transformations of betulin and its available derivatives are considered. The data on …

Therapeutic potential of glycyrrhetinic acids: a patent review (2010-2017)

H Hussain, IR Green, U Shamraiz… - Expert opinion on …, 2018 - Taylor & Francis
ABSTRACT Introduction: Glycyrrhetinic acids (GAs) viz., 18β-glycyrrhetinic acid and 18α-
glycyrrhetinic acid, are oleanane-type triterpenes having a carboxylic acid group at C-30 …

Controlled release of 18-β-glycyrrhetic acid by nanodelivery systems increases cytotoxicity on oral carcinoma cell line

I Cacciotti, L Chronopoulou, C Palocci… - …, 2018 - iopscience.iop.org
The topical treatment for oral mucosal diseases is often based on products optimized for
dermatologic applications; consequently, a lower therapeutic effect may be present. 18-β …

Prospects for the creation of new antiviral drugs based on glycyrrhizic acid and its derivatives (a review)

LA Baltina, RM Kondratenko, LA Baltina… - Pharmaceutical …, 2009 - Springer
The review is devoted to the problem of creating new antiviral drugs based on glycyrrhizic
acid (GA), the major triterpene glycoside extracted from roots of common and Ural licorice …

Enzymatic biotransformation of terpenes as bioactive agents

N Sultana, ZS Saify - Journal of enzyme inhibition and medicinal …, 2013 - Taylor & Francis
The plant-derived terpenoids are considered to be the most potent anticancer, anti-
inflammatory and anticarcinogenic compounds known. Enzymatic biotransformation is a …

Comparative study of selective in vitro and in silico BACE1 inhibitory potential of glycyrrhizin together with its metabolites, 18α-and 18β-glycyrrhetinic acid, isolated …

A Wagle, SH Seong, BT Zhao, MH Woo… - Archives of pharmacal …, 2018 - Springer
Abstract Hizikia fusiformis (Harvey) Okamura is a brown seaweed widely used in Korea and
Japan, and it contains different therapeutically active constituents. In the present study, we …

[HTML][HTML] Профессионально детерминированный образ жизни и здоровье врачей в условиях современной России

ВТ Кайбышев - Медицина труда и промышленная экология, 2006 - cyberleninka.ru
Представлены результаты анализа образа жизни и здоровья врачей, выполненного по
итогам анкетирования 6077 врачей Республики Башкортостан в 2002-2003 гг …

Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation

AV Markov, AV Sen'kova, D Warszycki… - Scientific Reports, 2017 - nature.com
Highly pathogenic influenza viruses pose a serious public health threat to humans. Although
vaccines are available, new antivirals are needed to efficiently control disease progression …