Oligonucleotides (ONs) are gaining increasing importance as a promising novel class of
biopharmaceuticals. Thanks to their fundamental role in gene regulation, they can be used …

Oligonucleotides have many important applications, including as primers in polymerase
chain reactions and probes for DNA sequencing. They are proposed as a diagnostic and …

Alkylamines are commonly used to improve both chromatographic and mass spectral
performance of electrospray ionization liquid chromatography mass spectrometry based …

In this study, we investigated the distribution behavior of single-stranded DNA molecules
with 20 bases in silica particles (particle size:∼ 30 μm) using confocal fluorescence …

Dipeptides of glycine and alanine were directly synthesized onto a silica surface using an
established procedure based on the fundamental principles of the Merrifield method. The …

We investigated the effects of the base number of single-stranded DNA and duplex DNA
formation on the intraparticle diffusion behavior in amino-functionalized silica particles. The …

A C18 column was modified with the anionic amino acid surfactant lauroyl-l-glutamate (LLG)
to facilitate the separation of ten short-chain aliphatic carboxylic acids (oxalic, tartaric, malic …

A well-known solvatochromic dye, Reichardt's dye (R-dye), was used to evaluate the
hydrophobicity of alkyl-group-functionalized silica particles (ASPs) with different chain …

We studied sequence-dependent retention properties of synthetic 5′-terminal phosphate
absent trinucleotides containing adenine, guanine and thymine through reversed-phase …

Oligonucleotides are short nucleic acid polymers used in research, genetic testing and
forensics. When used for these applications, they are generally made up to 13 to 25 …